Equine SAHH antibody and antigen (recombinant protein)

Diagnostic anti-Equine SAHH antibodies pairs and antigen for animal health (animal Equine/Horse S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-SAHH-Ag01Equine SAHH$3090.00
GMP-EQU-SAHH-Ab01Anti-Equine SAHH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-SAHH-Ab02Anti-Equine SAHH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-SAHH-Ab03Anti-Equine SAHH human monoclonal antibody (mAb)$3090.00
GMP-EQU-SAHH-Ab04Anti-Equine SAHH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-SAHH-Ag01
Product NameEquine SAHH
Target/BiomarkerEquine SAHH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine SAHH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of animal Equine/Horse with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
TagHis
Reconized/Reactive SpecicsEquine SAHH
Product descriptionRecombinant Equine SAHH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-SAHH-Ab01,GMP-EQU-SAHH-Ab02
Target/BiomarkerEquine SAHH
Product NameAnti-Equine SAHH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine SAHH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine SAHH antibodies in Equine SAHH level test of animal Equine/Horse with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
Product descriptionAnti-Equine SAHH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine SAHH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-SAHH-Ab03,GMP-EQU-SAHH-Ab04
Target/BiomarkerEquine SAHH
Product NameAnti-Equine SAHH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine SAHH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine SAHH antibodies in Equine SAHH level test of animal Equine/Horse with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
Product descriptionAnti-Equine SAHH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    S-Adenosylhomocysteine Hydrolase (SAHH) within the equine (horse) population embodies the intricate dance of biochemistry within these magnificent creatures. At its core, SAHH serves as a linchpin in the methylation cycle, a fundamental metabolic pathway essential for equine health.

    Structurally, SAHH is an enzyme with a pivotal role – the hydrolysis of S-Adenosylhomocysteine (SAH). SAH is a metabolic byproduct arising from methylation reactions, a process involved in the transfer of methyl groups to DNA, RNA, proteins, and other molecules. When SAH accumulates, it inhibits the activity of methyltransferase enzymes, which are responsible for DNA and RNA methylation, protein modifications, and the synthesis of neurotransmitters.

    SAHH acts as the enzyme that quells the potential chaos caused by excessive SAH. It cleaves SAH into adenosine and homocysteine, effectively preventing the buildup of SAH to inhibitory levels. This regulatory role is paramount, as it ensures that the methylation cycle continues to function harmoniously.

    SAHH's significance goes beyond its enzymatic function; it extends to the broader spectrum of equine biology. Methylation reactions are intricately tied to gene expression and regulation. When SAHH and the methylation cycle operate optimally, genes are appropriately activated or silenced, influencing the equine phenotype, physiology, and overall health.



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