Equine Tau antibody and antigen (recombinant protein)

Diagnostic anti-Equine Tau antibodies pairs and antigen for animal health (animal Equine/Horse Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-Tau-Ag01Equine Tau$3090.00
GMP-EQU-Tau-Ab01Anti-Equine Tau mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Tau-Ab02Anti-Equine Tau mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Tau-Ab03Anti-Equine Tau human monoclonal antibody (mAb)$3090.00
GMP-EQU-Tau-Ab04Anti-Equine Tau human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-Tau-Ag01
Product NameEquine Tau
Target/BiomarkerEquine Tau
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine Tau antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Tau level test of animal Equine/Horse with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsEquine Tau
Product descriptionRecombinant Equine Tau protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Tau-Ab01,GMP-EQU-Tau-Ab02
Target/BiomarkerEquine Tau
Product NameAnti-Equine Tau mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Tau antibodies in Equine Tau level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine Tau mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Tau antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Tau-Ab03,GMP-EQU-Tau-Ab04
Target/BiomarkerEquine Tau
Product NameAnti-Equine Tau human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Tau antibodies in Equine Tau level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine Tau mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Tau stands as a sentinel within the intricate landscape of equine neurobiology. This protein, primarily localized within the central nervous system (CNS) of horses, serves as a guardian of neuronal structural integrity and function. Its structural and functional homology to tau proteins in other species, including humans, underscores its critical role in maintaining proper neurological health.

    Structurally, Equine Tau belongs to the tau protein family, sharing commonalities with its counterparts in diverse organisms. Its primary function is to bind to microtubules within neurons, promoting their assembly and stability. Microtubules are essential cellular structures that facilitate axonal transport, synaptic plasticity, and overall neuronal communication.

    However, the equilibrium of tau proteins like Equine Tau can be disrupted in the context of neurodegenerative conditions observed in horses. Tau proteins may undergo post-translational modifications, including hyperphosphorylation. These modifications lead to tau proteins adopting atypical conformations, rendering them susceptible to aggregation. The aggregation of tau proteins culminates in the formation of neurofibrillary tangles within neurons. These tangles impede axonal transport, compromise synaptic function, and eventually result in neuronal dysfunction and degeneration.

    The presence of elevated levels of Equine Tau in specific contexts can serve as an indicator of these pathological processes, signaling the potential emergence of cognitive and neurological deficits in affected horses.



    About GDU


    GDU

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