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Feline AI antibody and antigen (recombinant protein)
Diagnostic anti-Feline AI antibodies pairs and antigen for animal health (animal Cat/Feline hypertension, renal disease, and congestive heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-FEL-AI-Ag01 | Feline AI | $3090.00 |
| GMP-FEL-AI-Ab01 | Anti-Feline AI mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-FEL-AI-Ab02 | Anti-Feline AI mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-FEL-AI-Ab03 | Anti-Feline AI human monoclonal antibody (mAb) | $3090.00 |
| GMP-FEL-AI-Ab04 | Anti-Feline AI human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-FEL-AI-Ag01 |
| Product Name | Feline AI |
| Target/Biomarker | Feline AI |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Feline AI antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AI level test of animal Cat/Feline with hypertension, renal disease, and congestive heart failure. |
| Tag | His | Reconized/Reactive Specics | Feline AI |
| Product description | Recombinant Feline AI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-FEL-AI-Ab01,GMP-FEL-AI-Ab02 |
| Target/Biomarker | Feline AI |
| Product Name | Anti-Feline AI mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Feline AI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline AI antibodies in Feline AI level test of animal Cat/Feline with hypertension, renal disease, and congestive heart failure. |
| Product description | Anti-Feline AI mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline AI antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-FEL-AI-Ab03,GMP-FEL-AI-Ab04 |
| Target/Biomarker | Feline AI |
| Product Name | Anti-Feline AI human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Feline AI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline AI antibodies in Feline AI level test of animal Cat/Feline with hypertension, renal disease, and congestive heart failure. |
| Product description | Anti-Feline AI mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Feline Amyloid A (fAA) stands as a complex and intricate biomarker that casts a radiant light on the health and well-being of our cherished domestic cats (Felis catus). In terms of its molecular structure, fAA belongs to the apolipoprotein family and assumes a role of paramount importance in the cat's immune defense system. Synthesized primarily within the feline liver, fAA emerges as an acute-phase protein, responding rapidly to inflammatory triggers, providing an eloquent testimony to the cat's immunological resilience.
In a more granular examination, fAA comprises a set of structural intricacies that resonate with its functional significance. It acts as a pentameric protein, composed of five identical subunits, each endowed with distinct responsibilities. When inflammation or infection rears its head, proinflammatory cytokines orchestrate the production of fAA in the liver. This orchestration results in a swift release of fAA into the bloodstream, peaking within the first 24 to 48 hours of the inflammatory event, a time frame that signifies a pivotal juncture in the immune response.
Beyond its presence as a diagnostic biomarker, fAA engages in a dynamic interplay with the feline immune system. One of its primary functions is that of an opsonin, a molecular facilitator that enhances the process of phagocytosis by immune cells, predominantly macrophages. By binding to damaged cells or invasive pathogens, fAA essentially flags them for efficient removal by immune effectors. Furthermore, fAA has the extraordinary ability to activate the classical complement pathway, augmenting the immune response's vigor and contributing to the removal of pathogens and immune complexes.
A deeper exploration into the scientific realm reveals the existence of genetic variations and isoforms of fAA, presenting a captivating avenue of research. These variations can provide profound insights into the genetic predisposition of cats to specific inflammatory conditions and offer potential therapeutic targets for precision medicine.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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