Feline BNP antibody and antigen (recombinant protein)

Diagnostic anti-Feline BNP antibodies pairs and antigen for animal health (animal Cat/Feline Cardiovascular Disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-BNP-Ag01Feline BNP$3090.00
GMP-FEL-BNP-Ab01Anti-Feline BNP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-BNP-Ab02Anti-Feline BNP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-BNP-Ab03Anti-Feline BNP human monoclonal antibody (mAb)$3090.00
GMP-FEL-BNP-Ab04Anti-Feline BNP human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-BNP-Ag01
Product NameFeline BNP
Target/BiomarkerFeline BNP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline BNP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in BNP level test of animal Cat/Feline with Cardiovascular Disease.
TagHis
Reconized/Reactive SpecicsFeline BNP
Product descriptionRecombinant Feline BNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-BNP-Ab01,GMP-FEL-BNP-Ab02
Target/BiomarkerFeline BNP
Product NameAnti-Feline BNP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline BNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline BNP antibodies in Feline BNP level test of animal Cat/Feline with Cardiovascular Disease.
Product descriptionAnti-Feline BNP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline BNP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-BNP-Ab03,GMP-FEL-BNP-Ab04
Target/BiomarkerFeline BNP
Product NameAnti-Feline BNP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline BNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline BNP antibodies in Feline BNP level test of animal Cat/Feline with Cardiovascular Disease.
Product descriptionAnti-Feline BNP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline B-type Natriuretic Peptide, commonly referred to as Feline BNP, assumes a central role in the intricate web of feline cardiovascular health. Synthesized predominantly within the ventricles of the heart in domestic cats (Felis catus), this peptide hormone is a key player in the regulation of blood pressure and fluid balance. It is part of the larger natriuretic peptide family, with atrial natriuretic peptide (ANP) as its companion, orchestrating the physiological symphony of cardiovascular stability.

    The production and release of Feline BNP are finely tuned processes, responsive to the demands placed on the feline heart. When the heart encounters increased pressure or volume overload, often due to conditions like congestive heart failure (CHF), valvular disease, or cardiomyopathy, the ventricles react by liberating Feline BNP into the bloodstream. This response serves as a natural mechanism to alleviate the cardiac workload and maintain blood pressure within the ideal range.

    The actions of Feline BNP are executed through its binding to specific receptors in the kidneys and blood vessels. This binding event initiates a cascade of events leading to increased excretion of sodium and water by the kidneys, promoting diuresis. This diuretic effect translates into a reduction in blood volume, a lightened burden on the heart, and the restoration of cardiovascular equilibrium.



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