Feline CBL antibody and antigen (recombinant protein)

Diagnostic anti-Feline CBL antibodies pairs and antigen for animal health (animal Cat/Feline ectopia lentis, learning difficulties and skeletal abnormalities) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-CBL-Ag01Feline CBL$3090.00
GMP-FEL-CBL-Ab01Anti-Feline CBL mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-CBL-Ab02Anti-Feline CBL mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-CBL-Ab03Anti-Feline CBL human monoclonal antibody (mAb)$3090.00
GMP-FEL-CBL-Ab04Anti-Feline CBL human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-CBL-Ag01
Product NameFeline CBL
Target/BiomarkerFeline CBL
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline CBL antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CBL level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
TagHis
Reconized/Reactive SpecicsFeline CBL
Product descriptionRecombinant Feline CBL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-CBL-Ab01,GMP-FEL-CBL-Ab02
Target/BiomarkerFeline CBL
Product NameAnti-Feline CBL mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline CBL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline CBL antibodies in Feline CBL level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Product descriptionAnti-Feline CBL mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline CBL antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-CBL-Ab03,GMP-FEL-CBL-Ab04
Target/BiomarkerFeline CBL
Product NameAnti-Feline CBL human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline CBL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline CBL antibodies in Feline CBL level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Product descriptionAnti-Feline CBL mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cobalamin, known colloquially as Vitamin B12 and represented by the biomarker CBL, is a remarkable biochemical cornerstone within the feline (cat) community. This water-soluble vitamin serves as an essential cog in numerous metabolic pathways that are fundamental to feline health and well-being.

    Structurally, Vitamin B12 features a complex molecular arrangement with a central cobalt atom. This cobalt atom is the linchpin of Vitamin B12's biological activity, crucial for its role as a coenzyme in enzymatic reactions vital to feline physiology.

    Vitamin B12 plays a pivotal role in the metabolic conversion of methylmalonyl-CoA to succinyl-CoA, catalyzed by methylmalonyl-CoA mutase. This conversion has far-reaching implications, as it contributes to the metabolism of amino acids and fatty acids. Additionally, Vitamin B12 participates in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methionine is a foundational amino acid, and its synthesis is indispensable for protein production and overall cellular function.

    Beyond its involvement in amino acid and fatty acid metabolism, Vitamin B12 is integral to DNA synthesis. Cats rely on Vitamin B12 for the production of thymidine, one of the four nucleotide building blocks of DNA. This role is foundational for growth, tissue repair, and overall feline development.

    Vitamin B12's significance extends to the production of myelin, the insulating sheath that envelops nerve fibers. Myelin ensures efficient transmission of nerve impulses, underpinning neurological function. Furthermore, Vitamin B12 plays a key role in heme synthesis, a vital component of hemoglobin within red blood cells. Hemoglobin's function in oxygen transport makes it central to feline vitality.



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