Feline cystatin C antibody and antigen (recombinant protein)

Diagnostic anti-Feline cystatin C antibodies pairs and antigen for animal health (animal Cat/Feline Hormone disorders) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-FEL-CysC-Ag01 cystatin C (CysC) $3090.00
GMP-FEL-CysC-Ab01 Anti-Feline cystatin C mouse monoclonal antibody (mAb) $3090.00
GMP-FEL-CysC-Ab02 Anti-Feline cystatin C mouse monoclonal antibody (mAb) $3090.00
GMP-FEL-CysC-Ab03 Anti-Feline cystatin C human monoclonal antibody (mAb) $3090.00
GMP-FEL-CysC-Ab04 Anti-Feline cystatin C human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-CysC-Ag01
Product Name cystatin C (CysC)
Target/Biomarker cystatin C (CysC)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline cystatin C antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cystatin C (CysC) level test of animal Cat/Feline with Hormone disorders.
Tag His
Reconized/Reactive Specics cystatin C (CysC)
Product description Recombinant Feline cystatin C protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-FEL-CysC-Ab01,GMP-FEL-CysC-Ab02
Target/Biomarker cystatin C (CysC)
Product Name Anti-Feline cystatin C mouse monoclonal antibody (mAb)
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Recombinant Feline cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies in cystatin C (CysC) level test of animal Cat/Feline with Hormone disorders.
Product description Anti-Feline cystatin C mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-FEL-CysC-Ab03,GMP-FEL-CysC-Ab04
Target/Biomarker cystatin C (CysC)
Product Name Anti-Feline cystatin C human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Feline cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies in cystatin C (CysC) level test of animal Cat/Feline with Hormone disorders.
Product description Anti-Feline cystatin C mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker Information


    Feline CYSC, or Cystatin C, is a modest-sized protein with outsized significance in the realm of feline health. This unassuming biomarker operates as a sentinel, a vigilant guardian of the intricate machinery within a cat's body, specifically, the renal system.

    Produced by cells throughout a cat's body at a consistent rate, Feline CYSC embarks on a journey that ultimately evaluates the health of the feline kidneys. Its voyage begins with the glomeruli, the intricate filtration units within the kidneys. Here, Feline CYSC is freely filtered from the blood, marking the initial step in assessing renal function.

    After traversing the glomeruli, Feline CYSC continues its odyssey through the renal tubules. Its fate is determined by the efficiency of glomerular filtration. In healthy cats, the majority of CYSC is reabsorbed and subsequently catabolized by the tubules. This intricate process ensures that CYSC levels in the bloodstream remain relatively stable, mirroring the efficiency of glomerular filtration.

    Feline CYSC's true strength lies in its sensitivity and specificity as a biomarker for renal health. Unlike traditional markers like creatinine, which can be influenced by variables such as muscle mass or diet, CYSC remains relatively immune to these factors. This makes CYSC a precise yardstick for evaluating renal function, especially in the early stages of kidney disease.

    Feline CYSC is the harbinger of proactive healthcare. Its ability to detect subtle shifts in renal function, even before overt clinical symptoms manifest, makes it an invaluable tool. Regular monitoring of CYSC levels can unveil renal issues in their infancy, allowing for timely intervention and a higher likelihood of successful treatment.

    The imperative to measure Feline CYSC transcends the boundaries of the laboratory; it embarks on a journey of profound scientific and clinical significance. This journey holds the promise of revolutionizing our approach to feline renal health, offering the potential to enhance the well-being and longevity of our feline companions.

    Feline CYSC serves as a linchpin in the assessment of glomerular filtration rate (GFR), a cornerstone of renal function. GFR represents the kidneys' ability to efficiently filter waste products, maintain fluid balance, and regulate electrolytes. In the intricate web of feline physiology, GFR is not just a metric; it is a lifeline that safeguards overall homeostasis.

    What sets Feline CYSC apart as a biomarker is its precision. It is a sensitive and specific indicator of renal function, especially in the early stages of renal disease. Unlike traditional markers like creatinine, which can be influenced by factors such as muscle mass or diet, Feline CYSC remains relatively immune to these confounders. This makes it a reliable tool for the early detection of kidney dysfunction.

    The clinical implications of Feline CYSC measurement are multifaceted. Firstly, it serves as a powerful diagnostic tool. Elevated CYSC levels act as an early warning signal, alerting veterinarians to the presence of renal dysfunction even before overt clinical symptoms manifest. Early detection is often the linchpin of successful intervention, improving the quality of life and extending the lifespan of feline patients.

    Beyond diagnosis, Feline CYSC guides the journey of disease management and therapeutic interventions. By regularly monitoring CYSC levels in cats with renal disease, veterinarians gain a dynamic view of disease progression. This allows them to tailor treatment strategies, optimizing medications, dietary plans, and fluid management to suit the unique needs of each feline patient. The result is not just an extension of lifespan but an enhancement of the quality of life for feline companions.

    Feline CYSC also serves as a beacon for scientific research. It offers a deeper understanding of renal function and dysfunction in cats, paving the way for innovative treatments and interventions. Researchers can delve into the intricacies of kidney disease, unraveling its molecular underpinnings and developing novel therapies guided by insights gleaned from CYSC measurements.

    In an era where preventive healthcare takes center stage, Feline CYSC emerges as a harbinger of proactive well-being. Regular monitoring of CYSC levels in apparently healthy cats can detect subtle shifts in renal function, allowing for preemptive measures to maintain kidney health and prevent the onset of disease.

    In conclusion, the measurement of Feline CYSC is a testament to the profound connection between science and the well-being of our feline companions. It illuminates the path to healthier cats, more effective treatments, and a deeper appreciation for the role of biomarkers in modern veterinary medicine.



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