Feline FER antibody and antigen (recombinant protein)

Diagnostic anti-Feline FER antibodies pairs and antigen for animal health (animal Cat/Feline hemochromatosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-FER-Ag01Feline FER$3090.00
GMP-FEL-FER-Ab01Anti-Feline FER mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-FER-Ab02Anti-Feline FER mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-FER-Ab03Anti-Feline FER human monoclonal antibody (mAb)$3090.00
GMP-FEL-FER-Ab04Anti-Feline FER human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-FER-Ag01
Product NameFeline FER
Target/BiomarkerFeline FER
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline FER antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FER level test of animal Cat/Feline with hemochromatosis.
TagHis
Reconized/Reactive SpecicsFeline FER
Product descriptionRecombinant Feline FER protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-FER-Ab01,GMP-FEL-FER-Ab02
Target/BiomarkerFeline FER
Product NameAnti-Feline FER mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline FER antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FER antibodies in Feline FER level test of animal Cat/Feline with hemochromatosis.
Product descriptionAnti-Feline FER mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FER antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-FER-Ab03,GMP-FEL-FER-Ab04
Target/BiomarkerFeline FER
Product NameAnti-Feline FER human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline FER antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline FER antibodies in Feline FER level test of animal Cat/Feline with hemochromatosis.
Product descriptionAnti-Feline FER mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    FER, the Fer protein, is a versatile and indispensable biomarker within the realm of cats (felines). This non-receptor tyrosine kinase is ubiquitously expressed across various feline tissues and cell types, exemplifying its profound significance in both normal physiological processes and pathological conditions.

    Structurally, FER features distinctive domains, including an N-terminal FER tyrosine kinase domain and a C-terminal domain specialized in protein-protein interactions. This molecular architecture equips FER with the ability to phosphorylate target proteins, orchestrating intricate intracellular signaling pathways. FER's multifaceted nature positions it as a key orchestrator of cellular functions in felines.

    A defining role of FER in felines is its involvement in the regulation of cell growth and proliferation. This non-receptor tyrosine kinase serves as a pivotal checkpoint in the complex signaling networks governing cellular division. When FER activity is perturbed or dysregulated, it can trigger uncontrolled cell growth, a cardinal feature of cancer. This aspect of FER biology holds profound implications for veterinary oncology. By measuring FER levels and scrutinizing its activity in feline tumors, clinicians can glean invaluable insights into cancer behavior, anticipate patient responses to treatments, and tailor therapeutic approaches for improved outcomes. Furthermore, ongoing investigations into FER's role in specific feline cancers may uncover novel therapeutic targets, bolstering the field of veterinary oncology.



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    GDU

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