Feline IgG antibody and antigen (recombinant protein)

Diagnostic anti-Feline IgG antibodies pairs and antigen for animal health (animal Cat/Feline) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-FEL-IgG-Ag01 Feline IgG $3090.00
GMP-FEL-IgG-Ab01 Anti-Feline IgG mouse monoclonal antibody (mAb) $3090.00
GMP-FEL-IgG-Ab02 Anti-Feline IgG mouse monoclonal antibody (mAb) $3090.00
GMP-FEL-IgG-Ab03 Anti-Feline IgG human monoclonal antibody (mAb) $3090.00
GMP-FEL-IgG-Ab04 Anti-Feline IgG human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-IgG-Ag01
Product Name Feline IgG
Target/Biomarker Feline IgG
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline IgG antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Feline IgG level test of animal Cat/Feline.
Tag His
Reconized/Reactive Specics Feline IgG
Product description Recombinant Feline IgG protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-FEL-IgG-Ab01,GMP-FEL-IgG-Ab02
Target/Biomarker Feline IgG
Product Name Anti-Feline IgG mouse monoclonal antibody (mAb)
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Recombinant Feline IgG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline IgG antibodies in Feline IgG level test of animal Cat/Feline.
Product description Anti-Feline IgG mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline IgG antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-FEL-IgG-Ab03,GMP-FEL-IgG-Ab04
Target/Biomarker Feline IgG
Product Name Anti-Feline IgG human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Feline IgG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline IgG antibodies in Feline IgG level test of animal Cat/Feline.
Product description Anti-Feline IgG mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker Information


    The measurement of Feline IgG levels transcends the boundaries of routine diagnostics; it serves as a gateway to unraveling the intricate dynamics of a cat's immune system, carrying profound implications for clinical practice and scientific inquiry.

    Within the clinical sphere, quantifying IgG levels holds pivotal importance for evaluating the health of a cat's immune system. A deficiency in IgG, termed hypogammaglobulinemia, can leave cats vulnerable to infections, compromising their ability to mount effective immune responses against pathogens. Monitoring IgG levels is instrumental in identifying and managing immunodeficiency disorders, allowing for timely interventions to enhance immune responses and protect the cat's well-being.

    Conversely, elevated IgG levels often signify an ongoing immune response, typically observed in the context of infections, inflammatory disorders, or autoimmune conditions. Measuring IgG levels provides crucial diagnostic insights, enabling veterinarians to pinpoint the underlying cause of a cat's clinical symptoms and design tailored treatment strategies.

    The quantification of Feline IgG also assumes paramount importance in assessing vaccine efficacy. Vaccination is a cornerstone of preventive veterinary medicine, and IgG levels serve as a reliable indicator of a cat's immune response to vaccines. By monitoring IgG titers following vaccination, veterinarians ensure that cats develop adequate protection against specific pathogens, thereby preventing and controlling highly contagious diseases.

    Furthermore, the measurement of Feline IgG has far-reaching implications in the domain of allergy diagnosis and management. Allergies in cats can manifest in multifarious ways, spanning from dermatological issues to gastrointestinal disturbances. Identifying the specific allergens responsible for these manifestations can be a complex undertaking. Nevertheless, by quantifying IgG antibodies against known allergens, veterinarians can systematically uncover the culprits, enabling targeted interventions and dietary modifications to alleviate the cat's discomfort.

    Beyond its clinical applications, the quantification of Feline IgG catalyzes scientific exploration in the realm of feline immunology. It furnishes researchers with a dynamic view of the cat's immune system, offering insights into immune responses triggered by infections, vaccinations, and environmental exposures. This treasure trove of data fuels the engine of veterinary research, empowering scientists to delve deeper into disease mechanisms, evaluate the efficacy of novel therapeutic modalities, and advance the frontiers of feline healthcare.

    In summation, the measurement of Feline IgG is more than a diagnostic tool; it is a portal to comprehensive feline healthcare and scientific enlightenment. Its clinical, research, and immunological implications converge to bolster the health and well-being of our feline companions, cementing Feline IgG's pivotal role in the tapestry of veterinary medicine and scientific discovery., Feline Immunoglobulin G (IgG) stands as a linchpin in the intricate framework of the feline immune system. Structurally, IgG is a glycoprotein characterized by its Y-shaped configuration, comprising two identical heavy chains and two identical light chains, held together by disulfide bonds. Each IgG molecule features antigen-binding regions of extraordinary specificity, finely tuned to recognize and bind to a diverse array of pathogens.

    The production of IgG antibodies in cats unfolds as a meticulously orchestrated process. When B cells, a subset of white blood cells, encounter antigens—foreign substances or pathogens—they undergo activation. Subsequently, these activated B cells transform into plasma cells, specialized factories dedicated to IgG production. These plasma cells churn out copious amounts of IgG antibodies, which are then released into the bloodstream.

    Feline IgG antibodies exhibit remarkable versatility and precision. They possess the ability to effectively recognize and bind to a wide spectrum of pathogens, including bacteria, viruses, fungi, and parasites, through their antigen-binding regions. This interaction serves multifaceted functions, from neutralizing the invaders to activating other immune cells, facilitating pathogen clearance, and marking pathogens for destruction.

    One of the extraordinary attributes of Feline IgG is its role in establishing long-lasting immunity. After an initial encounter with an antigen, memory B cells are generated. These memory B cells "remember" the specific pathogen, enabling the rapid production of IgG antibodies upon subsequent exposure to the same antigen. This mechanism underpins adaptive immunity, allowing cats to mount a swift and effective response upon reencountering a pathogen.



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