Feline PA antibody and antigen (recombinant protein)

Diagnostic anti-Feline PA antibodies pairs and antigen for animal health (animal Cat/Feline liver disease, inflammation, or tissue death) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-PA-Ag01Feline PA$3090.00
GMP-FEL-PA-Ab01Anti-Feline PA mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PA-Ab02Anti-Feline PA mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PA-Ab03Anti-Feline PA human monoclonal antibody (mAb)$3090.00
GMP-FEL-PA-Ab04Anti-Feline PA human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-PA-Ag01
Product NameFeline PA
Target/BiomarkerFeline PA
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline PA antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
TagHis
Reconized/Reactive SpecicsFeline PA
Product descriptionRecombinant Feline PA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PA-Ab01,GMP-FEL-PA-Ab02
Target/BiomarkerFeline PA
Product NameAnti-Feline PA mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PA antibodies in Feline PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
Product descriptionAnti-Feline PA mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PA antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PA-Ab03,GMP-FEL-PA-Ab04
Target/BiomarkerFeline PA
Product NameAnti-Feline PA human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PA antibodies in Feline PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
Product descriptionAnti-Feline PA mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Prothrombin Activation Fragment 1+2 (fPAF1+2) is a biochemical linchpin within the complex landscape of feline hemostasis. Structurally, it represents a fragment arising from the activation of prothrombin (Factor II) into thrombin (Factor IIa), a process governed by a cascade of coagulation factors and platelet interactions. This transformation is fundamental to the initiation of blood clot formation.

    Prothrombin, an inert precursor protein, circulates uneventfully in the feline bloodstream until the moment of vascular injury. When such an injury occurs, a choreographed sequence of enzymatic reactions ensues, culminating in the cleavage of prothrombin into two fragments: thrombin and fPAF1+2. Thrombin, the multifaceted enzyme that emerges from this process, occupies a pivotal role in the creation of a stable blood clot. It catalyzes the conversion of soluble fibrinogen into insoluble fibrin strands, which serve as the structural framework of a clot.

    While thrombin takes center stage in fibrin formation, fPAF1+2 assumes a different, yet equally critical, role. Rather than participating directly in clot assembly, it functions as an indispensable marker of ongoing thrombin generation within the feline hemostatic system. Its presence in the bloodstream serves as a dynamic reflection of the equilibrium between prothrombin activation and thrombin regulation.



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