Feline PG I antibody and antigen (recombinant protein)

Diagnostic anti-Feline PG I antibodies pairs and antigen for animal health (animal Cat/Feline atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-PG-I-Ag01Feline PG I$3090.00
GMP-FEL-PG-I-Ab01Anti-Feline PG I mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PG-I-Ab02Anti-Feline PG I mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PG-I-Ab03Anti-Feline PG I human monoclonal antibody (mAb)$3090.00
GMP-FEL-PG-I-Ab04Anti-Feline PG I human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-PG-I-Ag01
Product NameFeline PG I
Target/BiomarkerFeline PG I
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline PG I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
TagHis
Reconized/Reactive SpecicsFeline PG I
Product descriptionRecombinant Feline PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PG-I-Ab01,GMP-FEL-PG-I-Ab02
Target/BiomarkerFeline PG I
Product NameAnti-Feline PG I mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PG I antibodies in Feline PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Feline PG I mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PG I antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PG-I-Ab03,GMP-FEL-PG-I-Ab04
Target/BiomarkerFeline PG I
Product NameAnti-Feline PG I human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PG I antibodies in Feline PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Feline PG I mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cat/Feline Pepsinogen I (PG I) emerges as an intriguing biomarker, offering a window into the world of feline digestion. Structurally, PG I is an inactive zymogen, a precursor to the active enzyme pepsin, and it takes center stage in the gastric mucosa of the feline stomach. This biomolecule is primarily produced and secreted by chief cells, specialized exocrine cells nestled within the gastric glands.

    The journey of PG I begins with the ingestion of food. As dietary proteins enter the stomach, PG I awaits its transformation into pepsin. This metamorphosis unfolds within the acidic environment of the gastric lumen, catalyzed by the low pH. The conversion of PG I to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall feline health.

    Beyond its role as a digestive precursor, PG I serves as a sentinel for gastric health. The integrity of the gastric mucosa, where PG I is predominantly localized, is crucial for its proper secretion. Disruptions in this mucosal lining, such as those seen in gastritis or stomach ulcers, can alter PG I levels, offering valuable diagnostic clues.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.