Feline PTH antibody and antigen (recombinant protein)

Diagnostic anti-Feline PTH antibodies pairs and antigen for animal health (animal Cat/Feline Hyperparathyroidism) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-PTH-Ag01Feline PTH$3090.00
GMP-FEL-PTH-Ab01Anti-Feline PTH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PTH-Ab02Anti-Feline PTH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-PTH-Ab03Anti-Feline PTH human monoclonal antibody (mAb)$3090.00
GMP-FEL-PTH-Ab04Anti-Feline PTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-PTH-Ag01
Product NameFeline PTH
Target/BiomarkerFeline PTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline PTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Cat/Feline with Hyperparathyroidism.
TagHis
Reconized/Reactive SpecicsFeline PTH
Product descriptionRecombinant Feline PTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PTH-Ab01,GMP-FEL-PTH-Ab02
Target/BiomarkerFeline PTH
Product NameAnti-Feline PTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PTH antibodies in Feline PTH level test of animal Cat/Feline with Hyperparathyroidism.
Product descriptionAnti-Feline PTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-PTH-Ab03,GMP-FEL-PTH-Ab04
Target/BiomarkerFeline PTH
Product NameAnti-Feline PTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline PTH antibodies in Feline PTH level test of animal Cat/Feline with Hyperparathyroidism.
Product descriptionAnti-Feline PTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Parathyroid Hormone (fPTH) stands as a linchpin in the intricate web of endocrine regulation within the feline body. Structurally, it is a single-chain polypeptide hormone comprising 84 amino acids. Its primary site of synthesis and secretion resides in the parathyroid glands, four small, pea-sized structures discreetly positioned near the thyroid gland.

    The pivotal role of fPTH revolves around preserving the meticulous balance of calcium and phosphate in the feline bloodstream. The orchestration of this balance is essential for a myriad of physiological processes, including neuromuscular function, blood clotting, and cellular signaling.

    The very essence of fPTH's function lies in its responsiveness to alterations in ionized calcium levels. When blood calcium levels drop below the optimal range, specialized calcium-sensing receptors within the parathyroid glands spring into action. They trigger the secretion of fPTH, which sets off a cascade of events aimed at restoring calcium equilibrium.

    The primary target of fPTH's actions is the feline skeleton. Here, it exerts its influence by activating osteoclasts, specialized cells tasked with bone resorption. This process entails the breakdown of bone tissue, releasing stored calcium into the bloodstream. Simultaneously, fPTH tackles the issue of calcium excretion through the kidneys, where it fosters the reabsorption of calcium from urine, further conserving this vital mineral.

    Yet, fPTH's influence extends beyond these roles. It also collaborates with the gastrointestinal system by promoting the synthesis of calcitriol, the active form of vitamin D. Calcitriol, in turn, enhances the absorption of dietary calcium in the intestines, finalizing the loop of calcium regulation.



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