Feline PTH antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-FEL-PTH-Ag01	Recombinant Feline PTH protein	3090
GMP-FEL-PTH-Ab01	Anti-Feline PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-PTH-Ab02	Anti-Feline PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-PTH-Ab03	Anti-Feline PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-PTH-Ab04	Anti-Feline PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-FEL-PTH-Ag01
Product Name	Recombinant Feline PTH protein
Target/Biomarker	Feline parathyroid hormone (PTH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline parathyroid hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Cat/Feline with Hyperparathyroidism.
Tag	His
Products description	Recombinant Feline PTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-PTH-Ab01, GMP-FEL-PTH-Ab02, GMP-FEL-PTH-Ab03, GMP-FEL-PTH-Ab04
Product Name	Anti-Feline PTH mouse monoclonal antibody (mAb)
Target/Biomarker	Feline parathyroid hormone (PTH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Feline parathyroid hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Cat/Feline with Hyperparathyroidism.
Tag	mFc
Products description	Anti-Feline PTH mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Feline Parathyroid Hormone (fPTH) stands as a linchpin in the intricate web of endocrine regulation within the feline body. Structurally, it is a single-chain polypeptide hormone comprising 84 amino acids. Its primary site of synthesis and secretion resides in the parathyroid glands, four small, pea-sized structures discreetly positioned near the thyroid gland. The pivotal role of fPTH revolves around preserving the meticulous balance of calcium and phosphate in the feline bloodstream. The orchestration of this balance is essential for a myriad of physiological processes, including neuromuscular function, blood clotting, and cellular signaling. The very essence of fPTH's function lies in its responsiveness to alterations in ionized calcium levels. When blood calcium levels drop below the optimal range, specialized calcium-sensing receptors within the parathyroid glands spring into action. They trigger the secretion of fPTH, which sets off a cascade of events aimed at restoring calcium equilibrium. The primary target of fPTH's actions is the feline skeleton. Here, it exerts its influence by activating osteoclasts, specialized cells tasked with bone resorption. This process entails the breakdown of bone tissue, releasing stored calcium into the bloodstream. Simultaneously, fPTH tackles the issue of calcium excretion through the kidneys, where it fosters the reabsorption of calcium from urine, further conserving this vital mineral. Yet, fPTH's influence extends beyond these roles. It also collaborates with the gastrointestinal system by promoting the synthesis of calcitriol, the active form of vitamin D. Calcitriol, in turn, enhances the absorption of dietary calcium in the intestines, finalizing the loop of calcium regulation.

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