Feline Proinsulin antibody and antigen (recombinant protein)

Diagnostic anti-Feline Proinsulin antibodies pairs and antigen for animal health (animal Cat/Feline type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-Proinsulin-Ag01Feline Proinsulin$3090.00
GMP-FEL-Proinsulin-Ab01Anti-Feline Proinsulin mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Proinsulin-Ab02Anti-Feline Proinsulin mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Proinsulin-Ab03Anti-Feline Proinsulin human monoclonal antibody (mAb)$3090.00
GMP-FEL-Proinsulin-Ab04Anti-Feline Proinsulin human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-Proinsulin-Ag01
Product NameFeline Proinsulin
Target/BiomarkerFeline Proinsulin
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Proinsulin level test of animal Cat/Feline with type 2 diabetes.
TagHis
Reconized/Reactive SpecicsFeline Proinsulin
Product descriptionRecombinant Feline Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Proinsulin-Ab01,GMP-FEL-Proinsulin-Ab02
Target/BiomarkerFeline Proinsulin
Product NameAnti-Feline Proinsulin mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Proinsulin antibodies in Feline Proinsulin level test of animal Cat/Feline with type 2 diabetes.
Product descriptionAnti-Feline Proinsulin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Proinsulin antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Proinsulin-Ab03,GMP-FEL-Proinsulin-Ab04
Target/BiomarkerFeline Proinsulin
Product NameAnti-Feline Proinsulin human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Proinsulin antibodies in Feline Proinsulin level test of animal Cat/Feline with type 2 diabetes.
Product descriptionAnti-Feline Proinsulin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Proinsulin, an intricate 86-amino acid peptide hormone, occupies a pivotal position in the multifaceted dance of insulin biosynthesis within cats. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the beginning of the remarkable journey toward the production of insulin, the master regulator of glucose metabolism in cats.

    The voyage of Cat Proinsulin commences with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin undergoes a profound metamorphosis, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. Significantly, it is the presence of this C-peptide that sets proinsulin apart from mature insulin.

    During proinsulin processing, a meticulously choreographed sequence of enzymatic cleavage events takes place. Specific enzymes cleave the C-peptide from proinsulin, marking a critical transition in the process. This cleavage event transforms proinsulin into the active insulin molecule, which is then released into circulation, where it exerts its profound influence on glucose metabolism.

    The C-peptide, while often considered a byproduct of insulin processing, holds intrinsic value. It is not merely a structural element; it possesses physiological significance. Research suggests that the C-peptide may have independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest.



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    GDU

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