Feline S100-A8 antibody and antigen (recombinant protein)

Diagnostic anti-Feline S100-A8 antibodies pairs and antigen for animal health (animal Cat/Feline intestinal inflammation) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-S100-A8-Ag01Feline S100-A8$3090.00
GMP-FEL-S100-A8-Ab01Anti-Feline S100-A8 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A8-Ab02Anti-Feline S100-A8 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A8-Ab03Anti-Feline S100-A8 human monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A8-Ab04Anti-Feline S100-A8 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-S100-A8-Ag01
Product NameFeline S100-A8
Target/BiomarkerFeline S100-A8
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline S100-A8 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A8 level test of animal Cat/Feline with intestinal inflammation.
TagHis
Reconized/Reactive SpecicsFeline S100-A8
Product descriptionRecombinant Feline S100-A8 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-S100-A8-Ab01,GMP-FEL-S100-A8-Ab02
Target/BiomarkerFeline S100-A8
Product NameAnti-Feline S100-A8 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline S100-A8 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A8 antibodies in Feline S100-A8 level test of animal Cat/Feline with intestinal inflammation.
Product descriptionAnti-Feline S100-A8 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A8 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-S100-A8-Ab03,GMP-FEL-S100-A8-Ab04
Target/BiomarkerFeline S100-A8
Product NameAnti-Feline S100-A8 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline S100-A8 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A8 antibodies in Feline S100-A8 level test of animal Cat/Feline with intestinal inflammation.
Product descriptionAnti-Feline S100-A8 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline S100-A8, or Calgranulin A, is an extraordinary player in the complex orchestra of feline immune responses. It belongs to the S100 protein family, renowned for its calcium-binding properties and its central role in shaping immune reactions in cats.

    Structurally, Feline S100-A8 exists as a dimeric protein, composed of two subunits, each featuring two calcium-binding EF-hand motifs. This structural intricacy enables it to finely tune its responses to calcium fluctuations, a feature that plays a vital role in its immune-regulating functions.

    While predominantly found within immune cells, particularly neutrophils and monocytes, Feline S100-A8 also has a presence in non-immune cells, underscoring its versatility in modulating immune responses and inflammation.

    In response to immune activation, Feline S100-A8 can transition from an intracellular to an extracellular role. It is secreted into the extracellular environment, where it assumes its multifaceted role as a mediator of immune responses.

    One of its primary functions is to promote the recruitment of immune cells to sites of infection or tissue damage. Feline S100-A8 acts as a powerful chemoattractant, guiding immune cells precisely to the locations where their activities are required. Furthermore, it contributes to the phagocytosis of pathogens, enhancing the ability of immune cells to engulf and eliminate microbial invaders.

    In addition to its proinflammatory functions, Feline S100-A8 also emerges as a key player in the processes of tissue repair and regeneration. It actively participates in the restoration of damaged tissues following immune responses, an essential step for the resolution of inflammation and the return to normal tissue function.



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    GDU

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