Feline Serum amyloid A antibody and antigen (recombinant protein)

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Diagnostic anti-Feline Serum amyloid A antibodies pairs and antigen for animal health (animal Cat/Feline Acute inflammation, infections) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-Serum-amyloid-A-Ag01	Serum amyloid A	$3090.00
GMP-FEL-Serum-amyloid-A-Ab01	Anti-Feline Serum amyloid A mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-Serum-amyloid-A-Ab02	Anti-Feline Serum amyloid A mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-Serum-amyloid-A-Ab03	Anti-Feline Serum amyloid A human monoclonal antibody (mAb)	$3090.00
GMP-FEL-Serum-amyloid-A-Ab04	Anti-Feline Serum amyloid A human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-FEL-Serum-amyloid-A-Ag01
Product Name	Serum amyloid A
Target/Biomarker	Serum amyloid A
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Serum amyloid A antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Serum amyloid A level test of animal Cat/Feline with Acute inflammation, infections.
Tag	His
Reconized/Reactive Specics	Serum amyloid A
Product description	Recombinant Feline Serum amyloid A protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-Serum-amyloid-A-Ab01,GMP-FEL-Serum-amyloid-A-Ab02
Target/Biomarker	Serum amyloid A
Product Name	Anti-Feline Serum amyloid A mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Serum amyloid A antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Serum amyloid A antibodies in Serum amyloid A level test of animal Cat/Feline with Acute inflammation, infections.
Product description	Anti-Feline Serum amyloid A mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Serum amyloid A antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-Serum-amyloid-A-Ab03,GMP-FEL-Serum-amyloid-A-Ab04
Target/Biomarker	Serum amyloid A
Product Name	Anti-Feline Serum amyloid A human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Feline Serum amyloid A antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Serum amyloid A antibodies in Serum amyloid A level test of animal Cat/Feline with Acute inflammation, infections.
Product description	Anti-Feline Serum amyloid A mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

SAA, Serum Amyloid A, is a versatile and indispensable biomarker within the context of cats (felines). This protein assumes a central role in the feline immune system's response to inflammatory challenges. Primarily synthesized by hepatocytes in the liver, SAA is swiftly released into the bloodstream in response to various inflammatory signals, including those triggered by infections, tissue damage, or other inflammatory conditions.

Structurally, SAA comprises two primary isoforms in cats, SAA1 and SAA2, both of which can be elevated during inflammatory conditions. These isoforms play a pivotal role in modulating the host's immune response to pathogens and injuries. SAA acts as a chemoattractant for immune cells, facilitating their migration to the site of infection or inflammation. Additionally, SAA can influence other immune responses, including the production of cytokines and other inflammatory mediators.

In cats, SAA serves as a sensitive and early marker of systemic inflammation. When exposed to inflammatory stimuli, such as infections, tissue damage, or other inflammatory conditions, the liver rapidly increases the synthesis of SAA. Elevated levels of SAA in the bloodstream can be detected within hours of the initial trigger, making it a valuable diagnostic tool for veterinarians.

The measurement of SAA in cats transcends conventional biomarker assessment; it represents a cornerstone of feline healthcare and scientific inquiry. The multifaceted significance of SAA encompasses various aspects of veterinary medicine and research.

Firstly, SAA serves as a sentinel of inflammation in cats. Its rapid and robust response to inflammatory stimuli positions it as an indispensable diagnostic tool for veterinarians. Elevated SAA levels can indicate the presence of infectious diseases, inflammatory conditions, or tissue damage. The ability to detect such conditions early is instrumental in implementing timely interventions, initiating appropriate treatment strategies, and mitigating disease progression.

Secondly, SAA monitoring plays a pivotal role in disease management and treatment evaluation. By quantifying fluctuations in SAA levels over time, veterinarians can assess the effectiveness of therapeutic interventions. This dynamic monitoring enables timely adjustments to treatment plans, enhancing the likelihood of favorable outcomes for cats. Additionally, SAA measurements provide valuable insights into the severity of inflammation and the systemic impact of various feline diseases, aiding in disease stratification and treatment decision-making.

Beyond its diagnostic and therapeutic applications, SAA serves as a bridge between clinical veterinary practice and scientific research in cats. Ongoing investigations into SAA dynamics in different disease contexts expand our understanding of feline immunology and the intricate interplay between inflammation, infection, and tissue repair. These studies not only contribute to the advancement of feline healthcare but also pave the way for the development of innovative diagnostic and therapeutic strategies.

In conclusion, SAA in cats is more than a biomarker; it is a sentinel of inflammation, a linchpin in disease management, and a conduit for scientific exploration. The measurement of SAA in felines embodies the fusion of clinical veterinary expertise and cutting-edge scientific inquiry, ultimately promoting the health and well-being of feline populations worldwide.

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