Feline TSH antibody and antigen (recombinant protein)

Diagnostic anti-Feline TSH antibodies pairs and antigen for animal health (animal Cat/Feline Hypothyroidism, hyperthyroidism) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-TSH-Ag01Feline TSH$3090.00
GMP-FEL-TSH-Ab01Anti-Feline TSH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TSH-Ab02Anti-Feline TSH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TSH-Ab03Anti-Feline TSH human monoclonal antibody (mAb)$3090.00
GMP-FEL-TSH-Ab04Anti-Feline TSH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-TSH-Ag01
Product NameFeline TSH
Target/BiomarkerFeline TSH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline TSH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TSH level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
TagHis
Reconized/Reactive SpecicsFeline TSH
Product descriptionRecombinant Feline TSH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TSH-Ab01,GMP-FEL-TSH-Ab02
Target/BiomarkerFeline TSH
Product NameAnti-Feline TSH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline TSH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TSH antibodies in Feline TSH level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
Product descriptionAnti-Feline TSH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TSH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TSH-Ab03,GMP-FEL-TSH-Ab04
Target/BiomarkerFeline TSH
Product NameAnti-Feline TSH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline TSH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TSH antibodies in Feline TSH level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
Product descriptionAnti-Feline TSH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Thyroid-Stimulating Hormone (TSH), a pivotal biomarker in cats, occupies a central role in regulating the delicate balance of feline metabolic function. Structurally, TSH is a glycoprotein hormone consisting of two subunits, alpha and beta. Its production is orchestrated by the anterior pituitary gland in response to dynamic cues from the hypothalamic-pituitary-thyroid (HPT) axis.

    Within the HPT axis, TSH acts as the conductor of a metabolic orchestra. Its release is initiated by the hypothalamus, specifically via thyrotropin-releasing hormone (TRH) signaling. Low circulating levels of thyroid hormones, namely triiodothyronine (T3) and thyroxine (T4), serve as potent triggers for TSH production. When these hormones are insufficient, the anterior pituitary responds by producing and releasing TSH into the bloodstream.

    The journey of TSH then takes it to the thyroid gland, where it binds to specific receptors on the follicular cells. This binding event sets in motion a complex cascade of intracellular processes that culminate in the synthesis and secretion of thyroid hormones—T3 and T4. These hormones, in turn, exert far-reaching effects on feline metabolism, influencing everything from energy production to thermoregulation.

    The precision of this regulatory system is striking. When metabolic demands surge, such as during growth, pregnancy, or exposure to cold temperatures, TSH levels rise, urging the thyroid gland to produce more thyroid hormones. This orchestrated response boosts the metabolic rate, ensuring that the cat's body generates sufficient energy to meet its needs. Conversely, during periods of metabolic slowdown, TSH levels decrease, conserving energy and resources.



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