Feline Tau antibody and antigen (recombinant protein)

Diagnostic anti-Feline Tau antibodies pairs and antigen for animal health (animal Cat/Feline Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-Tau-Ag01Feline Tau$3090.00
GMP-FEL-Tau-Ab01Anti-Feline Tau mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Tau-Ab02Anti-Feline Tau mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Tau-Ab03Anti-Feline Tau human monoclonal antibody (mAb)$3090.00
GMP-FEL-Tau-Ab04Anti-Feline Tau human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-Tau-Ag01
Product NameFeline Tau
Target/BiomarkerFeline Tau
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline Tau antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Tau level test of animal Cat/Feline with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsFeline Tau
Product descriptionRecombinant Feline Tau protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Tau-Ab01,GMP-FEL-Tau-Ab02
Target/BiomarkerFeline Tau
Product NameAnti-Feline Tau mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Tau antibodies in Feline Tau level test of animal Cat/Feline with Alzheimer Disease(AD).
Product descriptionAnti-Feline Tau mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Tau antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Tau-Ab03,GMP-FEL-Tau-Ab04
Target/BiomarkerFeline Tau
Product NameAnti-Feline Tau human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Tau antibodies in Feline Tau level test of animal Cat/Feline with Alzheimer Disease(AD).
Product descriptionAnti-Feline Tau mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Tau stands as a linchpin in the intricate tapestry of feline neurobiology. This protein, primarily localized within the central nervous system (CNS) of cats, serves as a sentinel guarding neuronal structural integrity and function. Its structural and functional homology to tau proteins in other species, including humans, underscores its critical role in maintaining proper neurological health.

    Structurally, Feline Tau belongs to the tau protein family, sharing genetic and functional similarities with its counterparts in diverse organisms. Its primary function is to bind to microtubules within neurons, promoting their assembly and stability. Microtubules are essential for proper neuronal function, axonal transport, and synaptic communication.

    However, the equilibrium of tau proteins like Feline Tau can be disrupted in the context of neurodegenerative conditions observed in cats. Tau proteins may undergo post-translational modifications, including hyperphosphorylation. These modifications lead to tau proteins adopting atypical conformations, rendering them susceptible to aggregation. The aggregation of tau proteins culminates in the formation of neurofibrillary tangles within neurons. These tangles impede axonal transport, compromise synaptic function, and eventually result in neuronal dysfunction and degeneration.

    The presence of elevated levels of Feline Tau in specific contexts can serve as an indicator of these pathological processes, signaling the potential emergence of cognitive and neurological deficits in affected cats.



    About GDU


    GDU

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