2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-107-11. BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
2. Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody
$2709.00
GMP-SMT-107-21. OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
2. Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody
$2709.00
GMP-SMT-107-31. BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
2. Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) human monoclonal antibody
$2709.00
GMP-SMT-107-41. OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
2. Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) human monoclonal antibody
$2709.00
GMP-SMT-107-Ag-1BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)$756.00
GMP-SMT-107-Ag-2OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)$756.00
GMP-SMT-107-Ab-1Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody$1953.00
GMP-SMT-107-Ab-2Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)

Cat No.GMP-SMT-107-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) had been validated with our anti-Hapten antibody Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)

Cat No.GMP-SMT-107-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) had been validated with our anti-Hapten antibody Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody

Cat No.GMP-SMT-107-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)3-5
Products descriptionThe anti-Hapten antibody against hapten 2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) had been validated with our hapten hapten-carrier conjugates BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) human monoclonal antibody

Cat No.GMP-SMT-107-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)3-5
Products descriptionThe anti-Hapten antibody against hapten 2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) had been validated with our hapten hapten-carrier conjugates BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1. Chemical Structure and Functionality (Serial Number 1):

    2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) is a synthetic compound notable for its chemical structure, featuring a phenyl ring with three chlorine atoms attached. This structural arrangement imbues it with the properties of a synthetic auxin, a class of plant hormones crucial for regulating growth and development in plants. However, 2,4,5-T functions as a synthetic auxin disruptor, meaning it mimics the actions of natural auxins but does so in a way that disrupts normal plant growth processes. As a result, it triggers uncontrolled growth, wilting, and, ultimately, the death of the targeted plants.

    2. Selective Herbicidal Application (Serial Number 2):

    The unique mode of action of 2,4,5-T has rendered it a valuable tool in agriculture, horticulture, and forestry. It is primarily utilized as a selective herbicide, with a particular affinity for targeting broadleaf weeds while sparing grasses and other desirable plant species. This selectivity arises from the differential sensitivity of plant species to 2,4,5-T, making it effective in eliminating unwanted vegetation without harming crops or desired native plants.

    3. Notorious Role in Agent Orange (Serial Number 3):

    2,4,5-T gained notoriety for its inclusion as a key component in Agent Orange, a herbicidal defoliant utilized during the Vietnam War. The primary objective of employing Agent Orange was to defoliate dense vegetation in jungle terrains, thus reducing cover for enemy forces. This wartime application, however, came at a considerable cost. Agent Orange contained not only 2,4,5-T but also another herbicide called 2,4-D, and the production process resulted in the inadvertent inclusion of a highly toxic dioxin contaminant known as TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin).

    The legacy of Agent Orange use is marred by severe environmental repercussions, including long-lasting soil contamination and damage to aquatic ecosystems. Equally alarming are the adverse health effects experienced by individuals exposed to Agent Orange, including Vietnam War veterans and civilians residing in contaminated areas. Health issues associated with exposure include a range of cancers, birth defects, and neurological disorders.

    4. Environmental and Regulatory Concerns (Serial Number 4):

    Owing to mounting evidence of its environmental persistence, toxicity, and health risks, many nations have implemented stringent regulations or outright bans on the use of 2,4,5-T. These measures are aimed at mitigating its detrimental impact on ecosystems and human well-being.

    The environmental concerns stem from the compound's persistence in the environment, as it can take years to degrade fully. This persistence can result in its accumulation in soils and water bodies, posing a long-term risk to wildlife and aquatic ecosystems.

    5. Significance of Measurement (Serial Number 5):

    Environmental Assessment: The quantification of 2,4,5-T holds paramount importance for assessing its presence and concentration within ecosystems, particularly in regions with a historical application. Analyzing the residual levels of 2,4,5-T is essential for understanding its enduring impact on soil quality, water bodies, and the health of local vegetation. This information is integral to comprehensive environmental management and conservation efforts.

    Health and Safety Evaluation: The meticulous monitoring of 2,4,5-T levels is crucial for evaluating potential health and safety risks associated with exposure. Given its association with various adverse health effects in humans, including carcinogenicity and reproductive toxicity, quantifying its presence aids in the identification and mitigation of health concerns for individuals and communities.

    Regulatory Compliance: Adherence to regulations and guidelines governing the use of 2,4,5-T is another compelling reason for its measurement. Many countries have imposed restrictions or outright bans on the use of 2,4,5-T due to its environmental and health concerns. Regular monitoring is essential for ensuring compliance with these regulations, preventing unauthorized or illegal applications, and upholding public safety.

    Scientific Research and Remediation: In the realms of agriculture and environmental science, the measurement of 2,4,5-T is indispensable for research purposes. Researchers investigate its persistence in different environmental matrices, its behavior in ecosystems, and its long-term effects on both flora and fauna. This research informs strategies for environmental remediation in areas where 2,4,5-T contamination is a concern, facilitating the restoration of affected ecosystems.

    In conclusion, 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) plays a multifaceted role in herbicides and pesticides, with its historical association with Agent Orange being particularly notorious. The compound's measurement is pivotal for environmental assessment, health and safety evaluation, regulatory compliance, and scientific research. It serves as a critical tool in safeguarding ecosystems, human well-being, and compliance with regulations while fostering advancements in environmental science and management.



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