Metamizole  antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Metamizole  antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Metamizole 

OVA-Metamizole 

Anti-Metamizole  mouse monoclonal antibody

Anti-Metamizole  human monoclonal antibody

Reference

Data / case study

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Biomarker Information

1. Metamizole in In Vitro Diagnosis (IVD):

Introduction:

Metamizole, scientifically recognized as Dipyrone, stands as a synthetic small molecule of paramount significance in the realm of in vitro diagnosis (IVD). This versatile compound plays a pivotal role in various diagnostic applications within the biopharmaceutical domain. Our company specializes in offering a comprehensive suite of high-quality Metamizole antibodies and small molecule competitive antigens, meticulously tailored to meet the exacting demands of these specialized applications.

1.1 The Role of Metamizole in IVD:

Metamizole's primary function in IVD arises from its capacity to serve as a competitive antigen when conjugated with carrier molecules such as Bovine Serum Albumin (BSA) or Ovalbumin (OVA). These conjugates, referred to as immunogens or hapten-carrier conjugates, constitute indispensable components in the development of highly sensitive and specific immunoassays.

In immunoassays, Metamizole conjugates function as antigens that elicit an immune response when introduced into a biological sample. This response allows for the detection and quantification of specific antibodies or analytes in the sample, contributing to the precision and accuracy of diagnostic tests. These immunoassays find wide-ranging applications in clinical diagnostics, pharmaceutical research, and biomedical investigations.

2. The Significance of Measuring Metamizole:

2.1 Therapeutic Drug Monitoring (TDM):

Measuring Metamizole is of paramount importance for several compelling reasons. Firstly, Metamizole is a widely used analgesic and antipyretic medication, frequently administered to manage pain and reduce fever. To optimize therapeutic outcomes, it is essential to monitor Metamizole levels in patients. This practice helps healthcare professionals ensure that individuals receive the appropriate dosage, thereby mitigating the risks of overmedication or inadequate treatment. TDM of Metamizole contributes significantly to personalized medicine, enabling tailored drug regimens based on individual patient needs.

2.2 Toxicity Assessment:

Secondly, Metamizole has been associated with rare but severe adverse reactions, notably agranulocytosis. Regular monitoring of Metamizole levels assumes critical importance in healthcare settings as it allows for the early detection of potential toxicity issues in patients. By promptly identifying elevated Metamizole levels, healthcare providers can take necessary precautions and mitigate the risks associated with adverse drug reactions.

2.3 Compliance Monitoring:

Furthermore, within clinical contexts, it is crucial to verify patient adherence to prescribed medication regimens. Non-compliance can lead to treatment failures and suboptimal health outcomes. Measuring Metamizole levels provides a means to confirm patient compliance, as deviations from the expected drug concentration can indicate non-adherence. This information enables healthcare providers to engage with patients and address potential barriers to compliance, ultimately improving treatment outcomes.

2.4 Pharmacokinetics Studies:

Metamizole often serves as a model drug in pharmacokinetic investigations. Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted within the body. By measuring Metamizole levels at various time points after administration, researchers gain valuable insights into the drug's pharmacokinetic profile. This information is critical for understanding how Metamizole is processed by the body, guiding dosing regimens, and optimizing drug delivery strategies.

2.5 Quality Control in Immunoassays:

Lastly, Metamizole plays an indispensable role in immunoassay development for diverse diagnostic tests. Immunoassays rely on the precise and specific interaction between antigens and antibodies. Accurate quantification of Metamizole levels is fundamental to ensuring the robustness and precision of these assays. Our company's high-quality Metamizole antibodies and small molecule competitive antigens are essential components in the development of immunoassays that deliver accurate and reliable results, benefiting both clinical diagnostics and pharmaceutical research.

In conclusion, the quantification of Metamizole holds paramount importance in clinical and research domains. It encompasses multiple facets, including patient safety through therapeutic drug monitoring, the early detection of potential toxicity issues, confirmation of patient compliance, advancement of pharmacokinetic knowledge, and the facilitation of accurate and reliable diagnostic assays. Our company takes pride in providing top-tier antibodies and competitive antigens, specifically tailored for Metamizole detection. These products serve as critical tools in advancing healthcare and biopharmaceutical sectors, ensuring the utmost precision and effectiveness in diagnostic and therapeutic applications.

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