Antipyrine(AP) antibody/antigen (BSA/OVA/KLH conjugated hapten)

 Download 

anti-Antipyrine(AP) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

Go to Drugs of Abuse diagnostics products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Antipyrine(AP)

OVA-Antipyrine(AP)

Anti-Antipyrine(AP) mouse monoclonal antibody

Anti-Antipyrine(AP) human monoclonal antibody

Reference

Data / case study

Click to get more Data / Case study about the product.

Biomarker Information

Antipyrine (AP): A Versatile Component in In Vitro Diagnosis (IVD)

Antipyrine, also known by its scientific nomenclature phenazone, is a synthetic small molecule that has garnered significant recognition and utilization in the biopharmaceutical field. Its inherent stability, well-defined chemical structure, and compatibility with a range of analytical techniques have made it a prominent choice for various applications. In particular, Antipyrine holds a crucial role in the realm of in vitro diagnosis (IVD), impacting the accuracy, reliability, and standardization of diagnostic assays.

1.1 Structure and Chemical Properties

Antipyrine is characterized by a molecular structure consisting of a pyrazolone ring and three methyl groups. Its chemical properties include a melting point of approximately 113°C and a molecular weight of 188.2 g/mol. These attributes make Antipyrine amenable to various analytical methods, including spectrophotometry and immunoassays.

1.2 Role in In Vitro Diagnosis (IVD)

The significance of Antipyrine in IVD is multifaceted, encompassing several key aspects:

1.2.1 Calibration and Quality Assurance

Antipyrine serves as a reference molecule of choice for the calibration and quality assurance of IVD assays. This role is critical in ensuring the accuracy, precision, and reliability of diagnostic tests. By anchoring these tests to a known concentration of Antipyrine, healthcare professionals can have confidence in the consistency of results, irrespective of the laboratory or instrument used for analysis.

1.2.2 Assay Development and Validation

In the development and validation of immunoassays, Antipyrine emerges as a preferred competitive antigen. Its interaction with specific antibodies enables researchers to fine-tune assay performance. Through the study of the binding affinity between Antipyrine and these antibodies, sensitivity and specificity can be optimized. This process is vital for achieving diagnostic accuracy and minimizing false positives or negatives.

1.2.3 Standardization and Consistency

Antipyrine's inclusion as a calibrator or standard in IVD tests is pivotal for standardizing results across different laboratories and analytical platforms. Standardization is a cornerstone of IVD, ensuring that test outcomes can be meaningfully compared, leading to robust data interpretation and clinical decision-making.

1.2.4 Advancements in Research and Drug Development

Beyond its role in diagnostics, Antipyrine contributes significantly to pharmaceutical research. As a competitive antigen, it facilitates the exploration of antibody-antigen interactions. This insight, gained through the study of Antipyrine, informs our understanding of drug mechanisms and aids in the development of targeted therapies. Consequently, Antipyrine plays a vital role in advancing the biopharmaceutical field by serving as a model compound for studying these interactions and drug development processes.

1.3 Compatibility and Applications

Antipyrine's versatility extends to its compatibility with various analytical techniques, including high-performance liquid chromatography (HPLC) and enzyme-linked immunosorbent assays (ELISAs). This compatibility enhances its utility in both research and clinical settings. Researchers and healthcare providers can leverage Antipyrine to design experiments and diagnostic tests tailored to their specific needs.

1.4 Regulatory Compliance and Quality Control

The use of Antipyrine in IVD aligns with regulatory standards and requirements, ensuring that diagnostic assays meet the necessary quality control benchmarks. This adherence to regulatory guidelines is essential for obtaining approvals, certifications, and maintaining the highest standards of patient care.

1.5 Conclusion

In summary, Antipyrine, with its well-defined structure, stability, and versatility, plays an indispensable role in in vitro diagnosis (IVD) within the biopharmaceutical sector. From calibration and quality assurance to assay development, standardization, and advancing research and drug development, Antipyrine's multifaceted contributions underscore its pivotal status in healthcare and biopharmaceutical advancements. Its compatibility with a range of analytical methods ensures its relevance across diverse applications, promoting precision and reliability in diagnostics and research endeavors. Moreover, its compliance with regulatory standards assures the utmost quality control and patient-centric care in the ever-evolving landscape of biopharmaceuticals.

About GDU