Antipyrine(AP) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Antipyrine(AP) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-204-11. BSA-Antipyrine(AP)
2. Anti-Antipyrine(AP) mouse monoclonal antibody
$2709.00
GMP-SMT-204-21. OVA-Antipyrine(AP)
2. Anti-Antipyrine(AP) mouse monoclonal antibody
$2709.00
GMP-SMT-204-31. BSA-Antipyrine(AP)
2. Anti-Antipyrine(AP) human monoclonal antibody
$2709.00
GMP-SMT-204-41. OVA-Antipyrine(AP)
2. Anti-Antipyrine(AP) human monoclonal antibody
$2709.00
GMP-SMT-204-Ag-1BSA-Antipyrine(AP)$756.00
GMP-SMT-204-Ag-2OVA-Antipyrine(AP)$756.00
GMP-SMT-204-Ab-1Anti-Antipyrine(AP) mouse monoclonal antibody$1953.00
GMP-SMT-204-Ab-2Anti-Antipyrine(AP) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Antipyrine(AP)

Cat No.GMP-SMT-204-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Antipyrine(AP) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Antipyrine(AP) had been validated with our anti-Hapten antibody Anti-Antipyrine(AP) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Antipyrine(AP)

Cat No.GMP-SMT-204-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Antipyrine(AP) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Antipyrine(AP) had been validated with our anti-Hapten antibody Anti-Antipyrine(AP) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Antipyrine(AP) mouse monoclonal antibody

Cat No.GMP-SMT-204-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)3.00
Products descriptionThe anti-Hapten antibody against hapten Antipyrine(AP) had been validated with our hapten hapten-carrier conjugates BSA-Antipyrine(AP) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Antipyrine(AP) human monoclonal antibody

Cat No.GMP-SMT-204-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)3.00
Products descriptionThe anti-Hapten antibody against hapten Antipyrine(AP) had been validated with our hapten hapten-carrier conjugates BSA-Antipyrine(AP) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    Antipyrine (AP): A Versatile Component in In Vitro Diagnosis (IVD)

    Antipyrine, also known by its scientific nomenclature phenazone, is a synthetic small molecule that has garnered significant recognition and utilization in the biopharmaceutical field. Its inherent stability, well-defined chemical structure, and compatibility with a range of analytical techniques have made it a prominent choice for various applications. In particular, Antipyrine holds a crucial role in the realm of in vitro diagnosis (IVD), impacting the accuracy, reliability, and standardization of diagnostic assays.

    1.1 Structure and Chemical Properties

    Antipyrine is characterized by a molecular structure consisting of a pyrazolone ring and three methyl groups. Its chemical properties include a melting point of approximately 113°C and a molecular weight of 188.2 g/mol. These attributes make Antipyrine amenable to various analytical methods, including spectrophotometry and immunoassays.

    1.2 Role in In Vitro Diagnosis (IVD)

    The significance of Antipyrine in IVD is multifaceted, encompassing several key aspects:

    1.2.1 Calibration and Quality Assurance

    Antipyrine serves as a reference molecule of choice for the calibration and quality assurance of IVD assays. This role is critical in ensuring the accuracy, precision, and reliability of diagnostic tests. By anchoring these tests to a known concentration of Antipyrine, healthcare professionals can have confidence in the consistency of results, irrespective of the laboratory or instrument used for analysis.

    1.2.2 Assay Development and Validation

    In the development and validation of immunoassays, Antipyrine emerges as a preferred competitive antigen. Its interaction with specific antibodies enables researchers to fine-tune assay performance. Through the study of the binding affinity between Antipyrine and these antibodies, sensitivity and specificity can be optimized. This process is vital for achieving diagnostic accuracy and minimizing false positives or negatives.

    1.2.3 Standardization and Consistency

    Antipyrine's inclusion as a calibrator or standard in IVD tests is pivotal for standardizing results across different laboratories and analytical platforms. Standardization is a cornerstone of IVD, ensuring that test outcomes can be meaningfully compared, leading to robust data interpretation and clinical decision-making.

    1.2.4 Advancements in Research and Drug Development

    Beyond its role in diagnostics, Antipyrine contributes significantly to pharmaceutical research. As a competitive antigen, it facilitates the exploration of antibody-antigen interactions. This insight, gained through the study of Antipyrine, informs our understanding of drug mechanisms and aids in the development of targeted therapies. Consequently, Antipyrine plays a vital role in advancing the biopharmaceutical field by serving as a model compound for studying these interactions and drug development processes.

    1.3 Compatibility and Applications

    Antipyrine's versatility extends to its compatibility with various analytical techniques, including high-performance liquid chromatography (HPLC) and enzyme-linked immunosorbent assays (ELISAs). This compatibility enhances its utility in both research and clinical settings. Researchers and healthcare providers can leverage Antipyrine to design experiments and diagnostic tests tailored to their specific needs.

    1.4 Regulatory Compliance and Quality Control

    The use of Antipyrine in IVD aligns with regulatory standards and requirements, ensuring that diagnostic assays meet the necessary quality control benchmarks. This adherence to regulatory guidelines is essential for obtaining approvals, certifications, and maintaining the highest standards of patient care.

    1.5 Conclusion

    In summary, Antipyrine, with its well-defined structure, stability, and versatility, plays an indispensable role in in vitro diagnosis (IVD) within the biopharmaceutical sector. From calibration and quality assurance to assay development, standardization, and advancing research and drug development, Antipyrine's multifaceted contributions underscore its pivotal status in healthcare and biopharmaceutical advancements. Its compatibility with a range of analytical methods ensures its relevance across diverse applications, promoting precision and reliability in diagnostics and research endeavors. Moreover, its compliance with regulatory standards assures the utmost quality control and patient-centric care in the ever-evolving landscape of biopharmaceuticals.



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