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Histamine antibody and antigen (hapten, BSA/OVA conjugated)
Diagnostic anti-Histamine (Histamine) antibodies (anti-Histamine, anti-Histamine) and diagnostic hapten-carrier conjugates BSA-Histamine (Histamine), OVA-Histamine (Histamine), KLH-Histamine (Histamine) antigens for Inflammation/autoimmune/inflammatory disease Histamine detection in ELISA test, competitive ELISA, Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-SMT-222-Ag01 | BSA-Histamine | $756.00 |
| GMP-SMT-222-Ag02 | OVA-Histamine | $756.00 |
| GMP-SMT-222-Ab01 | Anti-human Histamine mouse monoclonal antibody (mAb) | $1953.00 |
| GMP-SMT-222-Ab02 | Anti-human Histamine human monoclonal antibody (mAb) | $1953.00 |
Size： 1mg | 10mg | 100mg
Product Description
BSA-Histamine
| Cat No. | GMP-SMT-222-Ag01 |
| Product Name | BSA-Histamine |
| Target | Histamine |
| Expression platform | Synthetic |
| Bioactivity validation | Histamine antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation |
| Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine / OVA-Histamine is Synthetic. |
| Purity | High (TBD) |
| Application | Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
OVA-Histamine
| Cat No. | GMP-SMT-222-Ag02 |
| Product Name | OVA-Histamine |
| Target | Histamine |
| Expression platform | Synthetic |
| Bioactivity validation | Histamine antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation |
| Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine / OVA-Histamine is Synthetic. |
| Purity | High (TBD) |
| Application | Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-human Histamine mouse monoclonal antibody (mAb)
| Cat No. | GMP-SMT-222-Ab01 |
| Product Name | Anti-human Histamine mouse monoclonal antibody (mAb) |
| Target | Histamine |
| Expression platform | hybridoma |
| Isotypes | Mouse IgG |
| Bioactivity validation | Histamine antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Histamine antibodies in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation. |
| Tag | mFc |
| Products description | Anti-human Histamine mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. |
| Purity | High (TBD) |
| Application | Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-human Histamine human monoclonal antibody (mAb)
| Cat No. | GMP-SMT-222-Ab02 |
| Product Name | Anti-human Histamine human monoclonal antibody (mAb) |
| Target | Histamine |
| Expression platform | hybridoma |
| Isotypes | Human IgG1 |
| Bioactivity validation | Histamine antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Histamine antibodies in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation. |
| Tag | hFc |
| Products description | Anti-human Histamine mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. |
| Purity | Purity: ≥95% （SDS-PAGE） |
| Application | Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker information
Histamine, a biogenic amine, is a small but potent molecule that plays diverse and crucial roles in the human body. Its presence and functions are intertwined with various physiological and pathological processes. Understanding histamine's multifaceted role is vital in the context of in vitro diagnosis (IVD) as it forms the basis for assessing and diagnosing conditions associated with its regulation.
Immunomodulation:
Histamine serves as a pivotal mediator of the immune system. Mast cells and basophils release histamine in response to allergens, pathogens, or injuries. This release triggers a cascade of immune responses, including inflammation, vasodilation, and the recruitment of immune cells to the site of action. In IVD, quantifying histamine levels is instrumental in identifying and monitoring allergic reactions, hypersensitivity disorders, and immune system aberrations.
Inflammatory Response:
Histamine is a key player in the inflammatory process. It induces vasodilation and increases vascular permeability, leading to the classic signs of inflammation: redness, swelling, and warmth. In the realm of IVD, monitoring histamine levels can be crucial for the diagnosis and management of inflammatory conditions such as rheumatoid arthritis or autoimmune diseases.
Gastric Regulation:
In the stomach, histamine stimulates the production of gastric acid, a critical component of the digestive process. Perturbations in histamine levels can contribute to gastrointestinal maladies, including gastritis and peptic ulcers. Consequently, assessing histamine levels plays a diagnostic and monitoring role in these gastrointestinal conditions.
Neurotransmission:
Histamine also functions as a neurotransmitter within the brain, influencing wakefulness, appetite regulation, and cognitive processes. Alterations in histamine levels can impact neurological functions, leading to sleep disturbances and conditions related to appetite regulation. In the context of IVD, measuring histamine levels can provide insights into neurological disorders and help diagnose conditions like narcolepsy or excessive daytime sleepiness.
Allergy Testing:
Histamine is a critical component of allergy testing. It serves as a positive control in allergy skin testing, helping healthcare professionals assess a patient's allergic response to specific allergens. This application is essential for the accurate diagnosis of allergies, guiding treatment and management strategies.
To summarize, histamine emerges as a versatile molecule, participating in a spectrum of physiological processes. These include immune response, inflammation, gastric regulation, and neurotransmission. Within the domain of IVD, quantifying histamine levels contributes to the diagnosis and monitoring of conditions closely associated with these functions. This enhances the capabilities of healthcare professionals, improves patient care, and informs research endeavors.
Genemedi offers a comprehensive array of antibodies and competitive antigens meticulously designed to enable precise histamine measurement. This, in turn, enhances the accuracy and dependability of diagnostic assays, research investigations, and the overall understanding of histamine's role in health and disease. With Genemedi's high-quality reagents, scientists and clinicians can confidently explore the intricate world of histamine and its implications in various medical conditions, thereby advancing the frontiers of healthcare and biomedical research.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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