Histamine antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Histamine antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Histamine

OVA-Histamine

Anti-Histamine mouse monoclonal antibody

Anti-Histamine human monoclonal antibody

Reference

Data / case study

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Biomarker Information

Histamine, a biogenic amine, is a bioactive compound naturally occurring in the human body, endowed with diverse physiological functions. Its primary roles encompass neurotransmission, immune response modulation, and regulation of gastric acid secretion. Histamine is a critical mediator of allergic reactions and inflammatory processes, playing an intricate role in orchestrating immune responses.

1. Histamine's Pertinence in in vitro diagnosis (IVD):

Within the realm of in vitro diagnosis (IVD), histamine assumes a pivotal role, particularly in assays designed to investigate allergic reactions and immunological phenomena. Histamine serves as a provocative agent in these diagnostic tests, provoking specific immune responses. This enables healthcare practitioners to discern hypersensitivity reactions to allergens and immune-related disorders with precision.

2. The Imperative of Histamine Quantification:

The quantification of histamine is a paramount endeavor for several compelling reasons:

- Allergy Diagnostics (1): Histamine provocation tests constitute an integral facet of allergy diagnostics. By quantifying the body's response to histamine exposure, clinicians can pinpoint allergenic triggers, enabling tailored therapeutic strategies for allergic patients.

- Immunological Investigations (2): Histamine's central role in the immune response renders its quantification indispensable in immunological research. Researchers utilize histamine measurements to elucidate the intricate dynamics of the immune system, fostering the development of therapeutic interventions for immune-related disorders.

- Gastrointestinal Pathologies (3): Excessive histamine release is implicated in certain gastrointestinal disorders, manifesting as symptoms like gastritis and ulcers. Monitoring histamine levels is pivotal in diagnosing and managing these conditions effectively.

- Pharmacological Inquiries (4): Histamine serves as a focal point in pharmaceutical research, particularly in the evaluation of drug efficacy and safety, notably in the context of antihistamine medications.

- Allergen Identification (5): Beyond allergy diagnosis, histamine measurements aid allergists and immunologists in pinpointing specific allergens responsible for triggering allergic reactions. This knowledge is invaluable for recommending targeted allergen avoidance strategies.

In summation, histamine's multifaceted role in immune responses, allergies, and gastrointestinal health underscores the critical importance of quantifying histamine levels in various diagnostic and research contexts. Such quantification empowers healthcare professionals and researchers to gain profound insights into patient health, immune system dynamics, and the development of efficacious therapeutic interventions.

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