Histamine (Histamine) antibody and antigen (hapten, BSA/OVA conjugated)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-SMT-222-Ag01	BSA-Histamine (Histamine)	756
GMP-SMT-222-Ag02	OVA-Histamine (Histamine)	756
GMP-SMT-222-Ab01	Anti-human Histamine (Histamine) mouse monoclonal antibody (mAb)	1953
GMP-SMT-222-Ab02	Anti-human Histamine (Histamine) human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-SMT-222-Ag01
Product Name	BSA-Histamine (Histamine)
Target/Biomarker	Histamine (Histamine)
Expression platform	Synthetic
Isotypes	NA
Bioactivity validation	Histamine (Histamine) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation.
Tag	NA
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine (Histamine) / OVA-Histamine (Histamine) is Synthetic.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-SMT-222-Ag02
Product Name	OVA-Histamine (Histamine)
Target/Biomarker	Histamine (Histamine)
Expression platform	Synthetic
Isotypes	NA
Bioactivity validation	Histamine (Histamine) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation.
Tag	NA
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine (Histamine) / OVA-Histamine (Histamine) is Synthetic.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-SMT-222-Ab01
Product Name	Anti-human Histamine (Histamine) mouse monoclonal antibody (mAb)
Target/Biomarker	Histamine (Histamine)
Expression platform	Hybridoma
Isotypes	Mouse IgG
Bioactivity validation	Histamine (Histamine) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation.
Tag	mFc
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine (Histamine) / OVA-Histamine (Histamine) is Synthetic.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Competitive immunoassay validation (Competitive ELISA),Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-SMT-222-Ab02
Product Name	Anti-human Histamine (Histamine) human monoclonal antibody (mAb)
Target/Biomarker	Histamine (Histamine)
Expression platform	Hybridoma
Isotypes	Mouse IgG
Bioactivity validation	Histamine (Histamine) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Histamine level test of Inflammation/autoimmune/inflammatory disease (allergic) and related syndrome evaluation.
Tag	mFc
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Histamine (Histamine) / OVA-Histamine (Histamine) is Synthetic.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Competitive immunoassay validation (Competitive ELISA),Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Histamine, a biogenic amine, is a small but potent molecule that plays diverse and crucial roles in the human body. Its presence and functions are intertwined with various physiological and pathological processes. Understanding histamine's multifaceted role is vital in the context of in vitro diagnosis (IVD) as it forms the basis for assessing and diagnosing conditions associated with its regulation. Immunomodulation: Histamine serves as a pivotal mediator of the immune system. Mast cells and basophils release histamine in response to allergens, pathogens, or injuries. This release triggers a cascade of immune responses, including inflammation, vasodilation, and the recruitment of immune cells to the site of action. In IVD, quantifying histamine levels is instrumental in identifying and monitoring allergic reactions, hypersensitivity disorders, and immune system aberrations. Inflammatory Response: Histamine is a key player in the inflammatory process. It induces vasodilation and increases vascular permeability, leading to the classic signs of inflammation: redness, swelling, and warmth. In the realm of IVD, monitoring histamine levels can be crucial for the diagnosis and management of inflammatory conditions such as rheumatoid arthritis or autoimmune diseases. Gastric Regulation: In the stomach, histamine stimulates the production of gastric acid, a critical component of the digestive process. Perturbations in histamine levels can contribute to gastrointestinal maladies, including gastritis and peptic ulcers. Consequently, assessing histamine levels plays a diagnostic and monitoring role in these gastrointestinal conditions. Neurotransmission: Histamine also functions as a neurotransmitter within the brain, influencing wakefulness, appetite regulation, and cognitive processes. Alterations in histamine levels can impact neurological functions, leading to sleep disturbances and conditions related to appetite regulation. In the context of IVD, measuring histamine levels can provide insights into neurological disorders and help diagnose conditions like narcolepsy or excessive daytime sleepiness. Allergy Testing: Histamine is a critical component of allergy testing. It serves as a positive control in allergy skin testing, helping healthcare professionals assess a patient's allergic response to specific allergens. This application is essential for the accurate diagnosis of allergies, guiding treatment and management strategies. To summarize, histamine emerges as a versatile molecule, participating in a spectrum of physiological processes. These include immune response, inflammation, gastric regulation, and neurotransmission. Within the domain of IVD, quantifying histamine levels contributes to the diagnosis and monitoring of conditions closely associated with these functions. This enhances the capabilities of healthcare professionals, improves patient care, and informs research endeavors. Genemedi offers a comprehensive array of antibodies and competitive antigens meticulously designed to enable precise histamine measurement. This, in turn, enhances the accuracy and dependability of diagnostic assays, research investigations, and the overall understanding of histamine's role in health and disease. With Genemedi's high-quality reagents, scientists and clinicians can confidently explore the intricate world of histamine and its implications in various medical conditions, thereby advancing the frontiers of healthcare and biomedical research.

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