Malassezia antibody and antigen (recombinant protein)

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Diagnostic anti-Malassezia antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine infectious disease skin disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P010-Tg001-Ag01	Recombinant Malassezia protein	$3090.00
GMP-VT-P010-Tg001-Ab01	Anti-Malassezia mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P010-Tg001-Ab02	Anti-Malassezia mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P010-Tg001-Ab03	Anti-Malassezia human monoclonal antibody (mAb)	$3090.00
GMP-VT-P010-Tg001-Ab04	Anti-Malassezia human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P010-Tg001-Ag01
Product Name	Recombinant Malassezia protein
Pathogen	Malassezia
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Malassezia antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Malassezia level test of animal Cat/Feline, Dog/Canine infectious disease with skin disease.
Tag	His
Product description	Recombinant Malassezia proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P010-Tg001-Ab01,GMP-VT-P010-Tg001-Ab02
Pathogen	Malassezia
Product Name	Anti-Malassezia mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Malassezia antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Malassezia antibodies in Malassezia level test of animal Cat/Feline, Dog/Canine infectious disease with skin disease.
Product description	Anti-Malassezia mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Malassezia antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P010-Tg001-Ab03,GMP-VT-P010-Tg001-Ab04
Pathogen	Malassezia
Product Name	Anti-Malassezia human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Malassezia antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Malassezia antibodies in Malassezia level test of animal Cat/Feline, Dog/Canine infectious disease with skin disease.
Product description	Anti-Malassezia mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Malassezia is a genus of fungi that are commonly found on human and animal skin. This eukaryotic fungus was previously known as Pityrosporum, which was later renamed Malassezia in honor of Louis-Charles Malassez, a French histologist who had studied yeast cells. Today, the Malassezia genus includes several species, such as Malassezia globosa, Malassezia restricta, and Malassezia furfur.

Malassezia is a Basidiomycota fungus. They are normally found as commensal organisms on the skin of humans and other animals. However, under certain circumstances, they can become pathogenic and cause various skin disorders, such as seborrheic dermatitis, atopic dermatitis, folliculitis, and pityriasis versicolor. These conditions pose a significant health concern and can cause discomfort and pain if left untreated.

The structure of Malassezia includes both yeast-like and mycelial forms. These different growth forms enable Malassezia spp. to adapt to different environments and help it to establish itself on host skin. Malassezia produces enzymes and proteins, including lipases and phospholipases, which contribute to its pathogenicity. They also produce substances that can affect the immune system and cause inflammation. Research suggests that certain species of Malassezia can trigger an immune response, leading to the development of skin disorders.

Malassezia primarily infects humans and other animals with hair follicles and sweat glands. The Malassezia species M. furfur commonly causes pityriasis versicolor, a skin infection that causes scaly, discolored patches on the skin. Seborrheic dermatitis, another common skin condition caused by Malassezia, affects the scalp, face, chest, upper back, and other oily areas of the body. It is characterized by redness, itching, and flaking of the skin.

Diagnostic methods for Malassezia infections involve microscopic examination of skin scrapings or culture of the organism from skin samples. These methods can identify the presence of the fungus and help determine the specific species causing the infection. For example, M. globosa is a common species found on human skin, while M. restricta is commonly associated with scalp conditions.

Nucleic acid-based tests, such as polymerase chain reaction (PCR), can be used to detect specific genes or genetic material associated with Malassezia. The internal transcribed spacer (ITS) region of the ribosomal DNA and the elongation factor-1 alpha (EF1α) gene are often targeted by these tests. These methods help to identify the presence of the fungus and its specific species causing the infection more accurately.

In conclusion, Malassezia is a genus of eukaryotic fungi that are commonly found on human and animal skin. Under certain circumstances, they can become pathogenic and cause various skin disorders. Research on Malassezia is ongoing, and further studies are needed to develop more accurate diagnostic methods and effective treatments for Malassezia-related skin conditions.

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