Canine Distemper Virus NP antibody and antigen (recombinant protein)

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Diagnostic anti-Canine Distemper Virus NP antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Fox, Wolf, Coyote, Skunk, Panda, Wolf, Ferret, Skunk, Raccoon, Pinniped, some primates infectious disease Canine distemper) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P012-Tg001-Ag01	Recombinant Canine Distemper Virus NP protein	$3090.00
GMP-VT-P012-Tg001-Ab01	Anti-Canine Distemper Virus NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P012-Tg001-Ab02	Anti-Canine Distemper Virus NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P012-Tg001-Ab03	Anti-Canine Distemper Virus NP human monoclonal antibody (mAb)	$3090.00
GMP-VT-P012-Tg001-Ab04	Anti-Canine Distemper Virus NP human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P012-Tg001-Ag01
Product Name	Recombinant Canine Distemper Virus NP protein
Pathogen	Canine Distemper Virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Distemper Virus NP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Canine Distemper Virus level test of animal Cat/Feline, Dog/Canine, Fox, Wolf, Coyote, Skunk, Panda, Wolf, Ferret, Skunk, Raccoon, Pinniped, some primates infectious disease with Canine distemper.
Tag	His
Product description	Recombinant Canine Distemper Virus NP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P012-Tg001-Ab01,GMP-VT-P012-Tg001-Ab02
Pathogen	Canine Distemper Virus
Product Name	Anti-Canine Distemper Virus NP mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Distemper Virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Distemper Virus antibodies in Canine Distemper Virus level test of animal Cat/Feline, Dog/Canine, Fox, Wolf, Coyote, Skunk, Panda, Wolf, Ferret, Skunk, Raccoon, Pinniped, some primates infectious disease with Canine distemper.
Product description	Anti-Canine Distemper Virus NP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Distemper Virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P012-Tg001-Ab03,GMP-VT-P012-Tg001-Ab04
Pathogen	Canine Distemper Virus
Product Name	Anti-Canine Distemper Virus NP human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Canine Distemper Virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Distemper Virus antibodies in Canine Distemper Virus level test of animal Cat/Feline, Dog/Canine, Fox, Wolf, Coyote, Skunk, Panda, Wolf, Ferret, Skunk, Raccoon, Pinniped, some primates infectious disease with Canine distemper.
Product description	Anti-Canine Distemper Virus NP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Canine distemper virus (CDV) is a highly contagious viral disease that affects domestic dogs and other carnivores, including foxes, raccoons, skunks, and wolves. The virus belongs to the paramyxoviridae family and has a single-stranded RNA genome that codes for six structural proteins. The disease caused by CDV is known as canine distemper.

The symptoms of canine distemper can vary from mild to severe and can affect multiple body systems, including respiratory, gastrointestinal, and neurological systems. The respiratory symptoms include coughing, sneezing, and discharge from the nose and eyes. The gastrointestinal symptoms include vomiting, diarrhea, and loss of appetite. The neurological symptoms include tremors, seizures, and paralysis. In severe cases, canine distemper can be fatal.

The diagnosis of canine distemper is based on clinical symptoms, serological testing, and molecular testing. Clinical symptoms alone may not be enough to confirm the diagnosis of CDV as they may be similar to other diseases. Serological testing involves detecting antibodies against the viral proteins such as H and F proteins using enzyme-linked immunosorbent assay (ELISA) or Western blotting techniques. Molecular testing involves detecting viral RNA using reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR. The most commonly targeted genes for molecular testing are the N and L genes of CDV.

Early diagnosis of CDV is essential for effective treatment and management of the disease. Treatment of canine distemper is mainly supportive, and there is no specific antiviral therapy available. Symptomatic treatment includes fluid therapy, antibiotics to treat secondary bacterial infections, anti-inflammatory drugs, and seizure control medication. Vaccination is the most effective way to prevent the spread of CDV. Puppies are usually vaccinated against canine distemper when they are six to eight weeks old and then every three to four weeks until they are 16 weeks old.

In conclusion, canine distemper is a highly contagious viral disease that affects domestic dogs and other carnivores. Accurate diagnosis of CDV is critical for effective treatment and prevention of the spread of this disease. Veterinary professionals should be aware of the current diagnostic methods available for CDV and should be prepared to utilize them in their clinical practice. Vaccination remains the most effective way to prevent the spread of CDV.

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