Canine Parainfluenza 2 Virus NP protein antibody and antigen (recombinant protein)

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Diagnostic anti-Canine Parainfluenza 2 Virus NP protein antibodies pairs and antigen for animal health (animal Dog/Canine infectious disease otitis media, pharyngitis, conjunctivitis, croup, tracheobronchitis, and pneumonia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P016-Tg001-Ag01	Recombinant Canine Parainfluenza 2 Virus NP protein protein	$3090.00
GMP-VT-P016-Tg001-Ab01	Anti-Canine Parainfluenza 2 Virus NP protein mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P016-Tg001-Ab02	Anti-Canine Parainfluenza 2 Virus NP protein mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P016-Tg001-Ab03	Anti-Canine Parainfluenza 2 Virus NP protein human monoclonal antibody (mAb)	$3090.00
GMP-VT-P016-Tg001-Ab04	Anti-Canine Parainfluenza 2 Virus NP protein human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P016-Tg001-Ag01
Product Name	Recombinant Canine Parainfluenza 2 Virus NP protein protein
Pathogen	Canine Parainfluenza 2 Virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Parainfluenza 2 Virus NP protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Canine Parainfluenza 2 Virus level test of animal Dog/Canine infectious disease with otitis media, pharyngitis, conjunctivitis, croup, tracheobronchitis, and pneumonia.
Tag	His
Product description	Recombinant Canine Parainfluenza 2 Virus NP protein proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P016-Tg001-Ab01,GMP-VT-P016-Tg001-Ab02
Pathogen	Canine Parainfluenza 2 Virus
Product Name	Anti-Canine Parainfluenza 2 Virus NP protein mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Parainfluenza 2 Virus NP protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Parainfluenza 2 Virus antibodies in Canine Parainfluenza 2 Virus level test of animal Dog/Canine infectious disease with otitis media, pharyngitis, conjunctivitis, croup, tracheobronchitis, and pneumonia.
Product description	Anti-Canine Parainfluenza 2 Virus NP protein mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Parainfluenza 2 Virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P016-Tg001-Ab03,GMP-VT-P016-Tg001-Ab04
Pathogen	Canine Parainfluenza 2 Virus
Product Name	Anti-Canine Parainfluenza 2 Virus NP protein human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Canine Parainfluenza 2 Virus NP protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Parainfluenza 2 Virus antibodies in Canine Parainfluenza 2 Virus level test of animal Dog/Canine infectious disease with otitis media, pharyngitis, conjunctivitis, croup, tracheobronchitis, and pneumonia.
Product description	Anti-Canine Parainfluenza 2 Virus NP protein mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Canine Parainfluenza 2 Virus (CPIV) is an important pathogen that primarily affects dogs. CPIV belongs to the Paramyxoviridae family, which includes several human and animal pathogens such as measles virus and respiratory syncytial virus. As a single-stranded RNA virus, CPIV is an obligate intracellular parasite that requires host cells for replication.

The genome of CPIV encodes for several structural and non-structural proteins, including the nucleoprotein (N), phosphoprotein (P), matrix protein (M), fusion protein (F), and hemagglutinin-neuraminidase protein (HN). These proteins play crucial roles in different stages of the viral life cycle, from attachment and entry into host cells to assembly and release of new virions.

CPIV primarily infects dogs but can also infect other canids such as coyotes and foxes. The virus causes an acute respiratory disease known as canine infectious tracheobronchitis or kennel cough. The clinical signs of kennel cough include dry, hacking cough, retching, and gagging, which can be particularly severe in young puppies or immunocompromised animals.

Several diagnostic methods are available to detect CPIV infection. Polymerase chain reaction (PCR)-based assays that amplify specific regions of the viral genome such as the N, F, or HN genes are widely used. Serological tests that detect CPIV-specific antibodies in blood samples are also commonly employed. Additionally, virus isolation can be achieved through culturing CPIV in susceptible cell lines and visualizing cytopathic effects under microscopy.

Prevention of CPIV infection is important to reduce the risk of disease transmission in dog populations. Vaccination is the most effective measure for preventing CPIV infection. Currently available vaccines contain inactivated or modified live virus and are administered subcutaneously or intranasally. Vaccination schedules vary based on the vaccine type, age, and risk of exposure.

Other preventive measures include good hygiene practices such as regular cleaning and disinfection of kennels and other high-risk areas. Additionally, minimizing stress and overcrowding can help reduce the risk of infection.

In conclusion, CPIV is an important pathogen that primarily affects dogs and can cause a severe respiratory disease known as kennel cough. Several diagnostic methods are available to detect CPIV infection, and prevention strategies include vaccination and good hygiene practices. Early detection and prompt treatment of infected animals can help prevent disease transmission and minimize the impact of CPIV on dog populations.

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