Chlamydophila abortus MOMP antibody and antigen (recombinant protein)

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Diagnostic anti-Chlamydophila abortus MOMP antibodies pairs and antigen for animal health (animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease Chlamydiosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P047-Tg003-Ag01	Recombinant Chlamydophila abortus MOMP protein	$3090.00
GMP-VT-P047-Tg003-Ab01	Anti-Chlamydophila abortus MOMP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P047-Tg003-Ab02	Anti-Chlamydophila abortus MOMP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P047-Tg003-Ab03	Anti-Chlamydophila abortus MOMP human monoclonal antibody (mAb)	$3090.00
GMP-VT-P047-Tg003-Ab04	Anti-Chlamydophila abortus MOMP human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P047-Tg003-Ag01
Product Name	Recombinant Chlamydophila abortus MOMP protein
Pathogen	Chlamydophila abortus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Chlamydophila abortus MOMP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Chlamydophila abortus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Chlamydiosis.
Tag	His
Product description	Recombinant Chlamydophila abortus MOMP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P047-Tg003-Ab01,GMP-VT-P047-Tg003-Ab02
Pathogen	Chlamydophila abortus
Product Name	Anti-Chlamydophila abortus MOMP mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Chlamydophila abortus MOMP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydophila abortus antibodies in Chlamydophila abortus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Chlamydiosis.
Product description	Anti-Chlamydophila abortus MOMP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydophila abortus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P047-Tg003-Ab03,GMP-VT-P047-Tg003-Ab04
Pathogen	Chlamydophila abortus
Product Name	Anti-Chlamydophila abortus MOMP human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Chlamydophila abortus MOMP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydophila abortus antibodies in Chlamydophila abortus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Chlamydiosis.
Product description	Anti-Chlamydophila abortus MOMP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Chlamydophila abortus, a Gram-negative, obligate intracellular bacterium, is a member of the family Chlamydiaceae. It is classified as a prokaryotic bacterium due to its lack of a true nucleus and other membrane-bound organelles. Chlamydophila abortus exhibits a unique biphasic developmental cycle consisting of two distinct forms, the elementary body (EB) and the reticulate body (RB).

The EB is the infectious but metabolically inactive form of the pathogen, and it plays a critical role in the transmission of the bacterium between hosts. The RB, on the other hand, is the non-infectious but metabolically active form, responsible for the replication of the pathogen within the host cell cytoplasm. The transformation from the EB to the RB form is triggered once the EB enters the host cell.

The major outer membrane protein (MOMP) is a prominent gene and protein found in Chlamydophila abortus, playing a crucial role in the initial attachment of the pathogen to the host cell. MOMP is known to contain both conserved and variable regions, which can be utilized for diagnostic purposes.

Enzootic abortion, also known as ovine enzootic abortion (OEA), is a bacterial infection caused by Chlamydophila abortus, affecting primarily domestic ruminant species like sheep and goats. Infected animals experience reproductive complications, including abortion, stillbirth, and the production of weak offspring. Enzootic abortion is a significant threat to the livestock industry, leading to economic losses in many countries worldwide.

In humans, exposure to Chlamydophila abortus through contact with infected animals or their by-products may result in flu-like symptoms or severe respiratory illness. The disease may manifest as an atypical pneumonia that can progress rapidly and is often associated with occupational exposure, such as veterinary work.

Diagnostic methods for Chlamydophila abortus are mainly molecular tests like PCR and nucleic acid hybridization assays that detect the presence of bacterial DNA in clinical samples. These tests often target genes associated with MOMP or other specific bacterial genes. Serological tests such as ELISA can detect Chlamydophila abortus-specific antibodies in infected animals' serum samples.

In summary, Chlamydophila abortus is an obligate intracellular bacterium that infects various animal species, including domestic ruminants, leading to reproductive complications such as enzootic abortion. In humans, exposure to Chlamydophila abortus may result in flu-like symptoms or severe respiratory illness. Diagnostic methods for this pathogen include both molecular and serological techniques that enable the identification of infected animals and potential carriers.

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