Mycoplasma pneumoniae antibody and antigen (recombinant protein)

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Diagnostic anti-Mycoplasma pneumoniae antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease respiratory disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P054-Tg002-Ag01	Recombinant Mycoplasma pneumoniae protein	$3090.00
GMP-VT-P054-Tg002-Ab01	Anti-Mycoplasma pneumoniae mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P054-Tg002-Ab02	Anti-Mycoplasma pneumoniae mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P054-Tg002-Ab03	Anti-Mycoplasma pneumoniae human monoclonal antibody (mAb)	$3090.00
GMP-VT-P054-Tg002-Ab04	Anti-Mycoplasma pneumoniae human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P054-Tg002-Ag01
Product Name	Recombinant Mycoplasma pneumoniae protein
Pathogen	Mycoplasma pneumoniae
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Mycoplasma pneumoniae antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Mycoplasma pneumoniae level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Tag	His
Product description	Recombinant Mycoplasma pneumoniae proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P054-Tg002-Ab01,GMP-VT-P054-Tg002-Ab02
Pathogen	Mycoplasma pneumoniae
Product Name	Anti-Mycoplasma pneumoniae mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Mycoplasma pneumoniae antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Mycoplasma pneumoniae antibodies in Mycoplasma pneumoniae level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Product description	Anti-Mycoplasma pneumoniae mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Mycoplasma pneumoniae antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P054-Tg002-Ab03,GMP-VT-P054-Tg002-Ab04
Pathogen	Mycoplasma pneumoniae
Product Name	Anti-Mycoplasma pneumoniae human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Mycoplasma pneumoniae antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Mycoplasma pneumoniae antibodies in Mycoplasma pneumoniae level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Product description	Anti-Mycoplasma pneumoniae mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Mycoplasma pneumoniae is a small, gram-negative, prokaryotic bacterium that lacks a cell wall and belongs to the class Mollicutes. As a result of its small genome, it produces only a limited number of proteins, with the adhesion protein P1 being one of its most significant. The pathogen colonizes the respiratory tract of its host due to the presence of the P1 protein, which allows it to attach to host cells, resulting in respiratory infections.

Mycoplasma pneumoniae is primarily known for causing illnesses related to the respiratory system, such as community-acquired pneumonia, bronchitis, and tracheobronchitis. These conditions are often mild and self-limiting but can be more severe, especially in individuals with weakened immune systems. Atypical pneumonia, as it is sometimes called, is a term used to describe pneumonia caused by Mycoplasma pneumoniae infections, whereby the symptoms are typically milder and longer-lasting than those of other forms of pneumonia.

When infected with Mycoplasma pneumoniae, the human body mounts an immune response, producing specific antibodies against the pathogen. Serological tests detect these antibodies within the blood and aid in the diagnosis of infections caused by M. pneumoniae. However, they are not reliable during the acute phase of infection. By contrast, nucleic acid amplification (NAA) techniques, such as polymerase chain reaction (PCR), target specific genes present in the pathogen's genome, identifying the pathogen's DNA sequence and serving as rapid diagnostic tools. Various gene targets of Mycoplasma pneumoniae have been investigated, including the P1 gene and the 16S rRNA gene. Additionally, methods such as loop-mediated isothermal amplification (LAMP) and real-time PCR have been developed recently, providing a more sensitive and specific diagnosis of the disease.

Culture is another diagnostic method for Mycoplasma pneumoniae. Like all Mollicutes, this bacterium requires specialized nutrients for growth, including sterols, which are not present in most commonly used bacterial culture media. As a result, specialized media must be utilized to culture Mycoplasma pneumoniae accurately.

To further confirm an infection caused by Mycoplasma pneumoniae, detection of specific proteins produced by the pathogen may be performed using enzyme-linked immunosorbent assay (ELISA) or immunoblotting techniques. For instance, the adhesion protein P1 can be detected through ELISA, confirming an infection caused by Mycoplasma pneumoniae.

In conclusion, Mycoplasma pneumoniae is a prokaryotic bacterium that primarily infects humans, causing respiratory illnesses such as atypical pneumonia, bronchitis, and tracheobronchitis. Its small genome and limited protein production make it resistant to antibiotics targeting bacterial cell walls. Serology, NAA, and culture techniques are diagnostic methods employed for Mycoplasma pneumoniae, each with their advantages and limitations. Detection of specific proteins produced by the pathogen is yet another way to diagnose an infection caused by Mycoplasma pneumoniae.

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