Bovine Parainfluenza-3 Virus (BPI3) NP antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Bovine Parainfluenza-3 Virus (BPI3) NP antibodies pairs and antigen for animal health (animal Bovines/Cattle infectious disease Bovine Parainfluenza-3 Virus (BPI3) infection) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Ruminants disease testing products collection >>

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P068-Tg001-Ag01	Recombinant Bovine Parainfluenza-3 Virus (BPI3) NP protein	$3090.00
GMP-VT-P068-Tg001-Ab01	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P068-Tg001-Ab02	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P068-Tg001-Ab03	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP human monoclonal antibody (mAb)	$3090.00
GMP-VT-P068-Tg001-Ab04	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P068-Tg001-Ag01
Product Name	Recombinant Bovine Parainfluenza-3 Virus (BPI3) NP protein
Pathogen	Bovine Parainfluenza-3 Virus (BPI3)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Bovine Parainfluenza-3 Virus (BPI3) level test of animal Bovines/Cattle infectious disease with Bovine Parainfluenza-3 Virus (BPI3) infection.
Tag	His
Product description	Recombinant Bovine Parainfluenza-3 Virus (BPI3) NP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P068-Tg001-Ab01,GMP-VT-P068-Tg001-Ab02
Pathogen	Bovine Parainfluenza-3 Virus (BPI3)
Product Name	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Parainfluenza-3 Virus (BPI3) NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Parainfluenza-3 Virus (BPI3) antibodies in Bovine Parainfluenza-3 Virus (BPI3) level test of animal Bovines/Cattle infectious disease with Bovine Parainfluenza-3 Virus (BPI3) infection.
Product description	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Parainfluenza-3 Virus (BPI3) antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P068-Tg001-Ab03,GMP-VT-P068-Tg001-Ab04
Pathogen	Bovine Parainfluenza-3 Virus (BPI3)
Product Name	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Bovine Parainfluenza-3 Virus (BPI3) NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Parainfluenza-3 Virus (BPI3) antibodies in Bovine Parainfluenza-3 Virus (BPI3) level test of animal Bovines/Cattle infectious disease with Bovine Parainfluenza-3 Virus (BPI3) infection.
Product description	Anti-Bovine Parainfluenza-3 Virus (BPI3) NP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen Information

Bovine Parainfluenza-3 Virus (BPI3) is a viral pathogen that primarily infects cattle. It was first identified in the 1950s and has since been recognized as an important cause of respiratory disease in both dairy and beef cattle worldwide.

BPI3 is an enveloped, negative-sense, single-stranded RNA virus that belongs to the family Paramyxoviridae and the genus Respirovirus. The virus is relatively large compared to other RNA viruses, with a diameter of approximately 150 nanometers. The virion is composed of several structural proteins, including the nucleoprotein (N), phosphoprotein, matrix protein, fusion (F) protein, and hemagglutinin-neuraminidase.

The BPI3 genome consists of several genes encoding various structural and non-structural proteins. The N gene encodes the major nucleocapsid protein, which is essential for virion assembly and genome replication. The F protein is responsible for mediating virus entry into host cells and is a key target for neutralizing antibodies. The hemagglutinin-neuraminidase protein is involved in virus attachment and release from infected cells.

BPI3 primarily infects cattle but can also infect other ruminants such as bison and buffalo. The virus is highly contagious and is transmitted primarily through direct contact with respiratory secretions from infected animals. Once inside a susceptible host, BPI3 replicates in the respiratory tract, causing damage to the airway epithelium and inducing an immune response. Clinical signs of BPI3 infection typically appear within 2-6 days after exposure and include fever, coughing, nasal discharge, and dyspnea. In addition, BPI3 infection can exacerbate pre-existing respiratory infections and lead to secondary bacterial infections, which can result in severe disease and even death.

The diagnosis of BPI3 infection is typically made by a combination of clinical signs, laboratory tests, and epidemiological data. Laboratory methods for detecting BPI3 include viral isolation, serological assays (such as ELISA), and molecular techniques like reverse transcription polymerase chain reaction (RT-PCR). These methods can target either the N gene or the F gene in order to detect viral RNA or measure host immune responses. Virus isolation involves the growth of BPI3 in cell culture followed by identification of the virus by cytopathic effects or immunofluorescence. Serological assays detect host antibodies against BPI3 using specific antigens, while RT-PCR detects viral RNA in respiratory secretions. Additionally, epidemiological data can be used to suggest that an outbreak of respiratory disease may be due to BPI3, particularly if characteristic clinical signs are observed in multiple animals in a herd.

Treatment of BPI3 infection typically involves supportive care, such as administration of fluids, anti-inflammatory drugs, and antibiotics to prevent secondary bacterial infections. However, there are currently no specific antiviral drugs available for treating BPI3 infection. Vaccines against BPI3 are commercially available and can help prevent the spread of the virus in herds. These vaccines typically contain inactivated or attenuated BPI3 virus and are administered by injection or intranasal spray.

In summary, Bovine Parainfluenza-3 Virus (BPI3) is a viral pathogen that primarily infects cattle and can cause respiratory disease with clinical signs including fever, coughing, nasal discharge, and dyspnea. The virus is highly contagious and can be transmitted through direct contact with respiratory secretions from infected animals. Diagnosis of BPI3 infection is typically made using a combination of clinical signs, laboratory tests, and epidemiological data. Treatment involves supportive care, while vaccination can help prevent the spread of the virus in herds.

About GDU