Porcine Respiratory Coronavirus S protein (spike protein) antibody and antigen (recombinant protein)

Diagnostic anti-Porcine Respiratory Coronavirus S protein (spike protein) antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease respiratory disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P132-Tg001-Ag01 Recombinant Porcine Respiratory Coronavirus S protein (spike protein) protein $3090.00
GMP-VT-P132-Tg001-Ab01 Anti-Porcine Respiratory Coronavirus S protein (spike protein) mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P132-Tg001-Ab02 Anti-Porcine Respiratory Coronavirus S protein (spike protein) mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P132-Tg001-Ab03 Anti-Porcine Respiratory Coronavirus S protein (spike protein) human monoclonal antibody (mAb) $3090.00
GMP-VT-P132-Tg001-Ab04 Anti-Porcine Respiratory Coronavirus S protein (spike protein) human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P132-Tg001-Ag01
Product Name Recombinant Porcine Respiratory Coronavirus S protein (spike protein) protein
Pathogen Porcine Respiratory Coronavirus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Porcine Respiratory Coronavirus S protein (spike protein) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Porcine Respiratory Coronavirus level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Tag His
Product description Recombinant Porcine Respiratory Coronavirus S protein (spike protein) proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P132-Tg001-Ab01,GMP-VT-P132-Tg001-Ab02
Pathogen Porcine Respiratory Coronavirus
Product Name Anti-Porcine Respiratory Coronavirus S protein (spike protein) mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Porcine Respiratory Coronavirus S protein (spike protein) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine Respiratory Coronavirus antibodies in Porcine Respiratory Coronavirus level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Product description Anti-Porcine Respiratory Coronavirus S protein (spike protein) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine Respiratory Coronavirus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P132-Tg001-Ab03,GMP-VT-P132-Tg001-Ab04
Pathogen Porcine Respiratory Coronavirus
Product Name Anti-Porcine Respiratory Coronavirus S protein (spike protein) human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Porcine Respiratory Coronavirus S protein (spike protein) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine Respiratory Coronavirus antibodies in Porcine Respiratory Coronavirus level test of animal Swine/Porcine/Pig infectious disease with respiratory disease.
Product description Anti-Porcine Respiratory Coronavirus S protein (spike protein) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen Information


    Porcine Respiratory Coronavirus (PRCV): A Comprehensive Overview

    Introduction:

    Porcine Respiratory Coronavirus (PRCV), a member of the Coronaviridae family, stands as a prominent viral pathogen affecting the swine industry. This comprehensive guide delves into the intricacies of PRCV, including its nomenclature, classification, structural components, host range, associated diseases, and diagnostic methods.

    Nomenclature:

    The scientific name of this pathogen is Porcine Respiratory Coronavirus. However, it's essential to note that PRCV is also known by synonyms, which include Transmissible Gastroenteritis Virus of Swine (TGEV) and Porcine Epidemic Diarrhea Virus (PEDV). These synonyms stem from the close genetic relationships and shared genetic material between these viruses.

    Classification:

    In the world of virology, PRCV is classified as a virus. Within the hierarchy of taxonomy, it belongs to the following categories:

    Family: Coronaviridae

    Order: Nidovirales

    Genus: Alphacoronavirus

    Pathogen Structure:

    At the heart of PRCV lies its genetic material, which is a single-stranded positive-sense RNA molecule. This genetic material encodes various proteins pivotal for the virus's replication and pathogenicity. Among these, four primary genes stand out:

    Spike (S) Gene: This gene encodes the spike protein, a fundamental component of PRCV. The spike protein plays a crucial role in the virus's ability to enter host cells, thus initiating the infection process.

    Envelope (E) Gene: The envelope protein, coded by the E gene, is integral for PRCV's assembly and release from host cells.

    Membrane (M) Gene: The M gene is responsible for coding the membrane protein, which aids in the formation of the viral envelope. The membrane protein plays an indispensable role in virus structure.

    Nucleocapsid (N) Gene: This gene encodes the nucleocapsid protein, which participates in the encapsulation of the viral RNA. The nucleocapsid protein is essential for RNA packaging and replication within host cells.

    Host Range and Associated Diseases:

    PRCV primarily infects domestic pigs, scientifically known as Sus scrofa domesticus. In the context of host species, PRCV is associated with a particular disease known as Porcine Respiratory Disease Complex (PRDC). PRDC is a multifactorial respiratory ailment that affects pigs. This condition is characterized by a combination of viral, bacterial, and environmental factors contributing to the severity of disease in affected animals. PRCV, alongside other pathogens, plays a role in the complex dynamics of PRDC, making it a significant concern in the swine industry.

    Diagnostic Methods:

    Accurate and timely diagnosis of PRCV is essential for effective disease management and control. Several diagnostic methods are employed to detect the presence of the virus:

    Polymerase Chain Reaction (PCR): PCR is a molecular technique used to amplify specific regions of the PRCV genome. This method allows for the identification of the virus's genetic material. Commonly targeted genes for PCR include the S gene, N gene, and other conserved regions.

    Reverse Transcription quantitative PCR (RT-qPCR): RT-qPCR is a valuable tool for the detection and quantification of PRCV RNA. This method involves reverse transcription to convert viral RNA into complementary DNA (cDNA) and then employs PCR to quantify the cDNA. Primers are designed to specifically target the S gene, N gene, or other conserved regions within the genome.

    Enzyme-Linked Immunosorbent Assay (ELISA): ELISA is an immunological assay employed to identify antibodies produced by the host's immune system in response to PRCV infection. The primary target of this method is often the spike protein (S), which elicits an immune response.

    In conclusion, Porcine Respiratory Coronavirus (PRCV) is a significant viral pathogen affecting the swine industry, primarily infecting domestic pigs and contributing to the complex dynamics of Porcine Respiratory Disease Complex (PRDC). Understanding its nomenclature, classification, structure, host range, associated diseases, and diagnostic methods is crucial for the effective management and control of this pathogen in the swine population. PRCV research and diagnostic techniques continue to evolve, contributing to the ongoing efforts to mitigate its impact on the swine industry.



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