Avian Rotavirus Group A&D vp6 antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Avian Rotavirus Group A&D vp6 antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease gastroenteritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Avian/Bird/Poultry disease testing products collection >>

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P160-Tg001-Ag01	Recombinant Avian Rotavirus Group A&D vp6 protein	$3090.00
GMP-VT-P160-Tg001-Ab01	Anti-Avian Rotavirus Group A&D vp6 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P160-Tg001-Ab02	Anti-Avian Rotavirus Group A&D vp6 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P160-Tg001-Ab03	Anti-Avian Rotavirus Group A&D vp6 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P160-Tg001-Ab04	Anti-Avian Rotavirus Group A&D vp6 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P160-Tg001-Ag01
Product Name	Recombinant Avian Rotavirus Group A&D vp6 protein
Pathogen	Avian Rotavirus Group A&D
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Avian Rotavirus Group A&D vp6 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Avian Rotavirus Group A&D level test of animal Avian/Bird/Poultry infectious disease with gastroenteritis.
Tag	His
Product description	Recombinant Avian Rotavirus Group A&D vp6 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P160-Tg001-Ab01,GMP-VT-P160-Tg001-Ab02
Pathogen	Avian Rotavirus Group A&D
Product Name	Anti-Avian Rotavirus Group A&D vp6 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Avian Rotavirus Group A&D vp6 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Rotavirus Group A&D antibodies in Avian Rotavirus Group A&D level test of animal Avian/Bird/Poultry infectious disease with gastroenteritis.
Product description	Anti-Avian Rotavirus Group A&D vp6 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Rotavirus Group A&D antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P160-Tg001-Ab03,GMP-VT-P160-Tg001-Ab04
Pathogen	Avian Rotavirus Group A&D
Product Name	Anti-Avian Rotavirus Group A&D vp6 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Avian Rotavirus Group A&D vp6 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Rotavirus Group A&D antibodies in Avian Rotavirus Group A&D level test of animal Avian/Bird/Poultry infectious disease with gastroenteritis.
Product description	Anti-Avian Rotavirus Group A&D vp6 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen Information

Avian Rotavirus Group A&D is a viral pathogen that belongs to the Reoviridae family. The virus is a non-enveloped, double-stranded RNA virus that primarily infects avian species, specifically poultry such as chickens and turkeys. The virus is known for causing enteritis, malabsorption syndrome, and diarrhea in young birds, which can lead to reduced weight gain, dehydration, and even death.

The genome of Avian Rotavirus Group A&D is made up of 11 segments of double-stranded RNA, which encode for six structural proteins and six non-structural proteins. Of these, the VP6 protein is the most abundant protein found in the virus particle. VP6 forms the inner capsid structure, which is responsible for protecting the RNA genome of the virus. In addition, VP6 protein interactions with host cells play crucial roles in the attachment and penetration of the virus into host cells.

VP4 and VP7 are two other essential structural proteins found on the surface of the virus particle. These proteins are responsible for the formation of the outer capsid layer, which plays a critical role in determining the serotype of the virus. The VP7 protein is the primary target for vaccination against rotaviruses worldwide.

Avian Rotavirus Group A&D infections commonly occur in young poultry, particularly chickens between two and five weeks old. These infections are acute and cause severe intestinal damage, leading to diarrhea, reduced feed efficiency, and increased mortality. In addition, the virus can lead to decreased egg production in infected hens, resulting in significant economic losses for poultry farmers.

Farmers typically use various diagnostic methods to detect the presence of Avian Rotavirus Group A&D infections. These methods include ELISA, RT-PCR, and RFLP analysis. ELISA is an immunological assay that detects specific rotavirus antigens. RT-PCR is a molecular biology technique used to amplify and detect specific segments of the viral RNA genome. Finally, RFPLP analysis involves digesting the amplified viral RNA with specific restriction enzymes, allowing for identification of unique banding patterns specific to the Avian Rotavirus Group A&D.

In conclusion, Avian Rotavirus Group A&D is a significant viral pathogen that can cause significant economic losses in the poultry industry. The virus primarily infects young birds and causes enteritis, malabsorption syndrome, and diarrhea. Although vaccines targeting VP7 have been developed, detection methods such as ELISA, RT-PCR, and RFLP remain essential for the diagnosis and control of Avian Rotavirus Group A&D infections in poultry.

About GDU