Infectious Laryngotracheitis Virus gB antibody and antigen (recombinant protein)

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Diagnostic anti-Infectious Laryngotracheitis Virus gB antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease infectious laryngotracheitis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P179-Tg001-Ag01	Recombinant Infectious Laryngotracheitis Virus gB protein	$3090.00
GMP-VT-P179-Tg001-Ab01	Anti-Infectious Laryngotracheitis Virus gB mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P179-Tg001-Ab02	Anti-Infectious Laryngotracheitis Virus gB mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P179-Tg001-Ab03	Anti-Infectious Laryngotracheitis Virus gB human monoclonal antibody (mAb)	$3090.00
GMP-VT-P179-Tg001-Ab04	Anti-Infectious Laryngotracheitis Virus gB human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P179-Tg001-Ag01
Product Name	Recombinant Infectious Laryngotracheitis Virus gB protein
Pathogen	Infectious Laryngotracheitis Virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Infectious Laryngotracheitis Virus gB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Infectious Laryngotracheitis Virus level test of animal Avian/Bird/Poultry infectious disease with infectious laryngotracheitis.
Tag	His
Product description	Recombinant Infectious Laryngotracheitis Virus gB proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P179-Tg001-Ab01,GMP-VT-P179-Tg001-Ab02
Pathogen	Infectious Laryngotracheitis Virus
Product Name	Anti-Infectious Laryngotracheitis Virus gB mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Infectious Laryngotracheitis Virus gB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Laryngotracheitis Virus antibodies in Infectious Laryngotracheitis Virus level test of animal Avian/Bird/Poultry infectious disease with infectious laryngotracheitis.
Product description	Anti-Infectious Laryngotracheitis Virus gB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Laryngotracheitis Virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P179-Tg001-Ab03,GMP-VT-P179-Tg001-Ab04
Pathogen	Infectious Laryngotracheitis Virus
Product Name	Anti-Infectious Laryngotracheitis Virus gB human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Infectious Laryngotracheitis Virus gB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Laryngotracheitis Virus antibodies in Infectious Laryngotracheitis Virus level test of animal Avian/Bird/Poultry infectious disease with infectious laryngotracheitis.
Product description	Anti-Infectious Laryngotracheitis Virus gB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

The Infectious Laryngotracheitis Virus (ILTV) is a highly contagious pathogen that primarily affects chickens, but also other poultry birds such as pheasants, partridges, and quails. ILTV is a member of the family Herpesviridae and the subfamily Alphaherpesvirinae. The virus is a non-segmented, linear, double-stranded DNA virus that encodes more than 100 genes, including the unique long (UL) and unique short (US) regions.

The virus has an envelope containing at least 12 viral glycoproteins that play a vital role in viral attachment, entry, and host range. The main structural glycoprotein, gC, is involved in virus adsorption and fusion with host cells. The UL52 gene encodes the ATPase subunit of the helicase-primase complex, which is essential for viral DNA replication.

ILTV infection is mainly transmitted through respiratory secretions and can present as a wide range of symptoms, including respiratory distress, conjunctivitis, nasal discharge, and high mortality rates. Mortality rates can be as high as 70% in unvaccinated chickens.

Several diagnostic methods are available to detect ILTV infection, including virus isolation, serological assays, histopathology, and nucleic acid-based detection methods. Virus isolation involves culturing the virus in embryonated chicken eggs or cell culture. Serological assays detect ILTV-specific antibodies in serum using ELISAs or serum neutralization assays. Histopathology involves examining tissues for characteristic lesions. Nucleic acid-based detection methods, such as polymerase chain reaction (PCR) and real-time quantitative PCR (qPCR), target specific viral genes such as UL52, gB, gE, and US9. Real-time qPCR is used to quantify viral load and monitor viral shedding in clinical samples.

In addition to diagnostics, control measures such as biosecurity, vaccination, and quarantine are essential for managing ILTV infection. Vaccination with live attenuated or inactivated vaccines can reduce the severity of clinical signs and mortality rates associated with ILTV infection.

In conclusion, ILTV is a highly contagious pathogen that primarily affects poultry birds such as chickens, pheasants, partridges, and quails. The disease caused by ILTV infection is called Infectious Laryngotracheitis (ILT) and can lead to respiratory distress, conjunctivitis, nasal discharge, and high mortality rates. Several diagnostic methods are available to detect ILTV infection, including virus isolation, serological assays, histopathology, and nucleic acid-based detection methods. Control measures such as biosecurity, vaccination, and quarantine are crucial for managing ILTV infection.

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