Fowlpox viruses FPV140 antibody and antigen (recombinant protein)

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Diagnostic anti-Fowlpox viruses FPV140 antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Fowlpox) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P208-Tg001-Ag01	Recombinant Fowlpox viruses FPV140 protein	$3090.00
GMP-VT-P208-Tg001-Ab01	Anti-Fowlpox viruses FPV140 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P208-Tg001-Ab02	Anti-Fowlpox viruses FPV140 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P208-Tg001-Ab03	Anti-Fowlpox viruses FPV140 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P208-Tg001-Ab04	Anti-Fowlpox viruses FPV140 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P208-Tg001-Ag01
Product Name	Recombinant Fowlpox viruses FPV140 protein
Pathogen	Fowlpox viruses
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Fowlpox viruses FPV140 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Fowlpox viruses level test of animal Avian/Bird/Poultry infectious disease with Fowlpox.
Tag	His
Product description	Recombinant Fowlpox viruses FPV140 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P208-Tg001-Ab01,GMP-VT-P208-Tg001-Ab02
Pathogen	Fowlpox viruses
Product Name	Anti-Fowlpox viruses FPV140 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Fowlpox viruses FPV140 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Fowlpox viruses antibodies in Fowlpox viruses level test of animal Avian/Bird/Poultry infectious disease with Fowlpox.
Product description	Anti-Fowlpox viruses FPV140 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Fowlpox viruses antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P208-Tg001-Ab03,GMP-VT-P208-Tg001-Ab04
Pathogen	Fowlpox viruses
Product Name	Anti-Fowlpox viruses FPV140 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Fowlpox viruses FPV140 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Fowlpox viruses antibodies in Fowlpox viruses level test of animal Avian/Bird/Poultry infectious disease with Fowlpox.
Product description	Anti-Fowlpox viruses FPV140 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Fowlpox virus is a highly infectious pathogen that belongs to the Poxviridae family. This virus primarily infects birds, particularly domesticated and wild species, and is commonly known as avian poxvirus or avipoxvirus. The Fowlpox virus genome consists of around 240,000 base pairs and encodes for over 200 genes.

In terms of classification, Fowlpox virus is considered a virus, which is a type of obligate intracellular parasite that requires a host cell to replicate. Additionally, this pathogen is double-stranded DNA virus that is capable of infecting both vertebrate and invertebrate hosts. The virus is composed of an outer envelope, a protein coat, and a core containing the viral DNA.

The viral envelope protein P4b plays an important role in the structure of the Fowlpox virus. This protein is involved in attaching the virus to host cells during the initial stages of infection. Additionally, P4b functions in the formation of the extracellular matrix, which provides support to the virus during its replication within the host cell.

Fowlpox virus can lead to a range of clinical presentations in birds, depending on the strain of the virus and the host species infected. Clinical signs of infection can vary from mild to severe and include skin lesions, oculonasal discharge, external and internal nodules on the head, respiratory distress, and even death.

Cutaneous pox is perhaps the most commonly observed presentation of Fowlpox virus infection. This form of the disease is characterized by the formation of dermal and epithelial lesions on various parts of the body, including the comb, wattles, and feet. These lesions usually start as small, red spots that gradually become more pronounced and eventually develop into raised, crusty nodules.

Another common presentation of Fowlpox virus infection is diphtheritic pox, which affects the respiratory and digestive tracts. This presentation of the disease is characterized by the formation of lesions in the mucous membranes of the respiratory and digestive tracts, resulting in breathing difficulties, coughing, sneezing, and difficulty swallowing.

Septicemic pox is a rare but serious form of Fowlpox virus infection that can lead to sepsis and even death in birds. In this presentation, the virus spreads throughout the body and causes a generalized systemic infection. Clinical signs include lethargy, depression, anorexia, and sudden death.

Diagnostic methods for Fowlpox virus include laboratory techniques such as PCR (polymerase chain reaction) and ELISA (enzyme-linked immunosorbent assay). These methods target various genes and proteins, including the P4b gene, the Poxvirus DNA polymerase gene, and the Fowlpox virus envelope protein.

In conclusion, Fowlpox virus is a highly infectious pathogen that primarily infects birds and can cause a range of presentations, including cutaneous pox, diphtheritic pox, and septicemic pox. The virus is classified as a double-stranded DNA virus and is composed of several components, including an outer envelope, a protein coat, and a core containing viral DNA. Diagnostic methods for Fowlpox virus include techniques that target specific genes and proteins.

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