Salmonella spp antibody and antigen (recombinant protein)

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Diagnostic anti-Salmonella spp antibodies pairs and antigen for animal health (animal Bovines/Cattle, Ovines/Sheep, Swine/Porcine/Pig infectious disease salmonellosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P238-Tg001-Ag01	Recombinant Salmonella spp protein	$3090.00
GMP-VT-P238-Tg001-Ab01	Anti-Salmonella spp mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P238-Tg001-Ab02	Anti-Salmonella spp mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P238-Tg001-Ab03	Anti-Salmonella spp human monoclonal antibody (mAb)	$3090.00
GMP-VT-P238-Tg001-Ab04	Anti-Salmonella spp human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P238-Tg001-Ag01
Product Name	Recombinant Salmonella spp protein
Pathogen	Salmonella spp
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Salmonella spp antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Salmonella spp level test of animal Bovines/Cattle, Ovines/Sheep, Swine/Porcine/Pig infectious disease with salmonellosis.
Tag	His
Product description	Recombinant Salmonella spp proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P238-Tg001-Ab01,GMP-VT-P238-Tg001-Ab02
Pathogen	Salmonella spp
Product Name	Anti-Salmonella spp mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Salmonella spp antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella spp antibodies in Salmonella spp level test of animal Bovines/Cattle, Ovines/Sheep, Swine/Porcine/Pig infectious disease with salmonellosis.
Product description	Anti-Salmonella spp mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella spp antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P238-Tg001-Ab03,GMP-VT-P238-Tg001-Ab04
Pathogen	Salmonella spp
Product Name	Anti-Salmonella spp human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Salmonella spp antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella spp antibodies in Salmonella spp level test of animal Bovines/Cattle, Ovines/Sheep, Swine/Porcine/Pig infectious disease with salmonellosis.
Product description	Anti-Salmonella spp mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Salmonella spp is a diverse group of bacterial pathogens that includes several species of bacteria. These bacteria are gram-negative and rod-shaped, belonging to the category of prokaryotes. Some members of the Salmonella spp group can cause diseases in a wide range of hosts, including animals and humans.

The pathogenicity of Salmonella spp is closely associated with its ability to secrete proteins through a Type III secretion system (T3SS). This system allows the bacteria to deliver virulence factors directly into host cells, leading to infection and disease. The T3SS comprises many genes and proteins, including invA, spaO, spaP, and prgH, which are involved in the assembly and regulation of the system. Notably, the expression of T3SS is regulated by HilA and HilD proteins.

Hosts infected with Salmonella spp are widespread and diverse, including humans, livestock, and wildlife. In humans, Salmonella infections are most commonly associated with gastroenteritis, or food poisoning. The symptoms of Salmonella gastroenteritis include nausea, vomiting, stomach cramps, and diarrhea, which may contain blood or mucus. Furthermore, Salmonella spp can cause typhoid fever, a severe illness characterized by high fever, weakness, abdominal pain, headache, and diarrhea. If left untreated, typhoid fever can be life-threatening.

In animals, Salmonella infections vary depending on the specific host species. For instance, in cattle, the bacteria can cause enteric diseases like salmonellosis. In pigs, Salmonella infections may result in reproductive failure, such as abortion and stillbirth. In chickens, Salmonella infections can lead to egg contamination, which is a significant public health concern.

To diagnose Salmonella spp infections, different methods can be used. Traditional microbiological techniques involve culturing the organism from the patient's clinical specimen, which can take up to several days. Serology tests may also be used to detect antibodies produced in response to Salmonella infection. However, these methods have low sensitivity and specificity. Alternatively, molecular methods such as PCR and DNA sequencing can provide rapid and accurate diagnosis. These methods target specific genes and proteins, including 16S rRNA gene, invA, spiA, and hilA. Additionally, immunological methods targeting specific Salmonella antigens can also detect the pathogen.

In conclusion, Salmonella spp represents a diverse group of bacterial pathogens that can cause diseases in humans and a wide range of animals. The key virulence factor of these bacteria is the Type III secretion system (T3SS), which allows them to deliver virulence factors into host cells. Salmonella spp infections are primarily associated with gastroenteritis or food poisoning in humans, while other animal species may exhibit distinct symptoms. Various diagnostic methods, including traditional microbiological techniques and molecular and immunological methods, are available to detect Salmonella spp infections.

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