Alpha-1-microglobulin (A1M) antibody and antigen (Recombinant protein)

Diagnostic Alpha-1-microglobulin (A1M) antibodies (anti-Alpha-1-microglobulin, anti-A1M) and antigens (recombinant Alpha-1-microglobulin (A1M) protein) for Kidney function (renal damages) A1M detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-A1M-Ag01 Recombinant human A1M Protein $3090.00
GMP-h-A1M-Ab01 Anti-human A1M mouse monoclonal antibody (mAb) $1953.00
GMP-h-A1M-Ab02 Anti-human A1M mouse monoclonal antibody (mAb) $1953.00
GMP-h-A1M-Ab03 Anti-human A1M human monoclonal antibody (mAb) $1953.00
GMP-h-A1M-Ab04 Anti-human A1M human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-A1M-Ag01
Product Name Recombinant human A1M Protein
Target/Biomarker Alpha-1-microglobulin (A1M)
Alias of Target/Biomarker A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Alpha-1-microglobulin (A1M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation
Products description Recombinant Human Alpha-1-microglobulin (A1M) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-A1M-Ab01,GMP-h-A1M-Ab02
Product Name Anti-human A1M mouse monoclonal antibody (mAb)
Target/Biomarker Alpha-1-microglobulin (A1M)
Alias of Target/Biomarker A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation.
Tag mFc
Products description Anti-human A1M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-A1M-Ab03,GMP-h-A1M-Ab04
Product Name Anti-human A1M human monoclonal antibody (mAb)
Target/Biomarker Alpha-1-microglobulin (A1M)
Alias of Target/Biomarker A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation.
Tag hFc
Products description Anti-human A1M mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker information

    Urinary microproteins are becoming increasingly important in clinical diagnostics. They can contribute in the non-invasive early detection of renal abnormalities and the differentiation of various nephrological and urological pathologies. Alpha-1-microglobulin (A1M, α1-microglobulin, sometimes also called Protein HC) is a microglobulin, a small globular protein. It is found in all vertebrates, including humans, and is distributed in blood plasma and extravascular tissues of all organs. It is synthesized in most cells of the body, but mainly in the liver from a gene that codes for the alpha-1-microglobulin/bikunin precursor. A1M can be used as an indicator of proteinuria. The test can be regarded as positive when the ratio of A1M (in milligrams) and creatinine in millimoles in the urine is over 0.7 mg/mmol. A test for preeclampsia, where A1M serves as the diagnostic marker, has been proposed. It is based upon the fact that oxidative stress in the placenta tissue triggers the endogenous synthesis and plasma concentration of the protein.Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.



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