Alpha-1-microglobulin (A1M) antibody and antigen (Recombinant protein)
Diagnostic Alpha-1-microglobulin (A1M) antibodies (anti-Alpha-1-microglobulin, anti-A1M) and antigens (recombinant Alpha-1-microglobulin (A1M) protein) for Kidney function (renal damages) A1M detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-h-A1M-Ag01 | Recombinant human A1M Protein | $3090.00 |
GMP-h-A1M-Ab01 | Anti-human A1M mouse monoclonal antibody (mAb) | $1953.00 |
GMP-h-A1M-Ab02 | Anti-human A1M mouse monoclonal antibody (mAb) | $1953.00 |
GMP-h-A1M-Ab03 | Anti-human A1M human monoclonal antibody (mAb) | $1953.00 |
GMP-h-A1M-Ab04 | Anti-human A1M human monoclonal antibody (mAb) | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. of Pruducts | GMP-h-A1M-Ag01 |
Product Name | Recombinant human A1M Protein |
Target/Biomarker | Alpha-1-microglobulin (A1M) |
Alias of Target/Biomarker | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC |
Expression platform | mammalian |
Isotypes | Recombinant Antigen |
Bioactivity validation | Alpha-1-microglobulin (A1M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation |
Products description | Recombinant Human Alpha-1-microglobulin (A1M) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Pruducts | GMP-h-A1M-Ab01,GMP-h-A1M-Ab02 |
Product Name | Anti-human A1M mouse monoclonal antibody (mAb) |
Target/Biomarker | Alpha-1-microglobulin (A1M) |
Alias of Target/Biomarker | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation. |
Tag | mFc |
Products description | Anti-human A1M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies. |
Reconized/Reactive Species | Human |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Pruducts | GMP-h-A1M-Ab03,GMP-h-A1M-Ab04 |
Product Name | Anti-human A1M human monoclonal antibody (mAb) |
Target/Biomarker | Alpha-1-microglobulin (A1M) |
Alias of Target/Biomarker | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation. |
Tag | hFc |
Products description | Anti-human A1M mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Reconized/Reactive Species | Human |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
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Target/Biomarker information
Urinary microproteins are becoming increasingly important in clinical diagnostics. They can contribute in the non-invasive early detection of renal abnormalities and the differentiation of various nephrological and urological pathologies. Alpha-1-microglobulin (A1M, α1-microglobulin, sometimes also called Protein HC) is a microglobulin, a small globular protein. It is found in all vertebrates, including humans, and is distributed in blood plasma and extravascular tissues of all organs. It is synthesized in most cells of the body, but mainly in the liver from a gene that codes for the alpha-1-microglobulin/bikunin precursor. A1M can be used as an indicator of proteinuria. The test can be regarded as positive when the ratio of A1M (in milligrams) and creatinine in millimoles in the urine is over 0.7 mg/mmol. A test for preeclampsia, where A1M serves as the diagnostic marker, has been proposed. It is based upon the fact that oxidative stress in the placenta tissue triggers the endogenous synthesis and plasma concentration of the protein.Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.
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