β-isomerized C-terminal telopeptides (β-CTx) antibody and antigen (Recombinant protein)

Diagnostic β-isomerized C-terminal telopeptides (β-CTx) antibodies (anti-β-isomerized C-terminal telopeptides, anti-β-CTx) and antigens (recombinant β-isomerized C-terminal telopeptides (β-CTx) protein) for Metabolic diseases β-CTx detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

Target products collectionGo to Metabolic diseases diagnostics products collection >>



Product information

Catalog No. Description US $ Price (per mg)
GMP-h-CTx-Ag01 Recombinant human β-CTx Protein $3090.00
GMP-h-CTx-Ab01 Anti-human β-CTx mouse monoclonal antibody (mAb) $1953.00
GMP-h-CTx-Ab02 Anti-human β-CTx mouse monoclonal antibody (mAb) $1953.00
GMP-h-CTx-Ab03 Anti-human β-CTx human monoclonal antibody (mAb) $1953.00
GMP-h-CTx-Ab04 Anti-human β-CTx human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-CTx-Ag01
Product Name Recombinant human β-CTx Protein
Target/Biomarker β-isomerized C-terminal telopeptides (β-CTx)
Alias of Target/Biomarker #N/A
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation β-isomerized C-terminal telopeptides (β-CTx) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in β-CTx level test of Metabolic diseases (osteoporosis) and related syndrome evaluation
Products description Recombinant Human β-isomerized C-terminal telopeptides (β-CTx) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-CTx-Ab01,GMP-h-CTx-Ab02
Product Name Anti-human β-CTx mouse monoclonal antibody (mAb)
Target/Biomarker β-isomerized C-terminal telopeptides (β-CTx)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human β-isomerized C-terminal telopeptides (β-CTx) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other β-isomerized C-terminal telopeptides (β-CTx) antibodies in β-CTx level test of Metabolic diseases (osteoporosis) and related syndrome evaluation.
Tag mFc
Products description Anti-human β-CTx mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other β-isomerized C-terminal telopeptides (β-CTx) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-CTx-Ab03,GMP-h-CTx-Ab04
Product Name Anti-human β-CTx human monoclonal antibody (mAb)
Target/Biomarker β-isomerized C-terminal telopeptides (β-CTx)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human β-isomerized C-terminal telopeptides (β-CTx) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other β-isomerized C-terminal telopeptides (β-CTx) antibodies in β-CTx level test of Metabolic diseases (osteoporosis) and related syndrome evaluation.
Tag hFc
Products description Anti-human β-CTx mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data

    Picture loading failed.

    Figure 1. GeneMedi's GMP-h-β-CTx-Ab01/02/03/04 (Anti-human β-CTx mouse monoclonal antibody) are validated to detect the GMP-h-β-CTx-Ag01 (Recombinant human β-CTx Protein) in ELISA.

       EC50 [Ab01 (capture)-Ab02 (detect) ]= 271.3 ppb;

       EC50 [Ab01 (capture)-Ab04 (detect)]= 614.8 ppb;

       EC50 [Ab03 (capture)-Ab02 (detect) ]= 363.5 ppb;

       EC50 [Ab03 (capture)-Ab04 (detect) ]= 811.8 ppb.


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Bone is a metabolically active tissue, and almost 10% of the human adult bone is remodeled every year. Bone remodeling comprises bone resorption and formation. During the remodeling process, the activity of osteoblasts and osteoclasts results in the release of proteins or peptides. The peptide products are either proteins released by the cells, such as bone-specific alkaline phosphatase (BAP) and osteocalcin (OC) or degradation products of cellular activity, such as urinary hydroxyproline, deoxypyridinoline, β-isomerized C-terminal telopeptides (β-CTx), total procollagen type 1 amino-terminal propeptide (tP1NP), etc [14]. The measurement of these clinical biomarkers, categorized as biochemical bone markers, in serum and urine is widely used as a rapid means to monitor cellular activity of bone [15]. β-CTx and other substances that originate during bone resorption are called bone resorption markers, while tP1NP, BAP, and OC, which are generated from bone reconstruction, are called bone formation markers.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

    Comments


    No comments yet.

    Leave a comment