Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibody and antigen (Recombinant protein)

Diagnostic Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies (anti-Heat shock proteins 90-alpha (HSP90α), anti-HSP90α) and antigens (recombinant Heat shock proteins 90-alpha (HSP90α) (HSP90α) protein) for Cancer HSP90α detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-HSP90-Ag01 Recombinant human HSP90α Protein $3090.00
GMP-h-HSP90-Ab01 Anti-human HSP90α mouse monoclonal antibody (mAb) $1953.00
GMP-h-HSP90-Ab02 Anti-human HSP90α mouse monoclonal antibody (mAb) $1953.00
GMP-h-HSP90-Ab03 Anti-human HSP90α human monoclonal antibody (mAb) $1953.00
GMP-h-HSP90-Ab04 Anti-human HSP90α human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-HSP90-Ag01
Product Name Recombinant human HSP90α Protein
Target/Biomarker Heat shock proteins 90-alpha (HSP90α)
Alias of Target/Biomarker #N/A
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HSP90α level test of Cancer (renal cancer, liver cancer and breast cancer) and related syndrome evaluation
Products description Recombinant Human Heat shock proteins 90-alpha (HSP90α) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-HSP90-Ab01,GMP-h-HSP90-Ab02
Product Name Anti-human HSP90α mouse monoclonal antibody (mAb)
Target/Biomarker Heat shock proteins 90-alpha (HSP90α)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Heat shock proteins 90-alpha (HSP90α) (HSP90α) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies in HSP90α level test of Cancer (renal cancer, liver cancer and breast cancer) and related syndrome evaluation.
Tag mFc
Products description Anti-human HSP90α mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-HSP90-Ab03,GMP-h-HSP90-Ab04
Product Name Anti-human HSP90α human monoclonal antibody (mAb)
Target/Biomarker Heat shock proteins 90-alpha (HSP90α)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Heat shock proteins 90-alpha (HSP90α) (HSP90α) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies in HSP90α level test of Cancer (renal cancer, liver cancer and breast cancer) and related syndrome evaluation.
Tag hFc
Products description Anti-human HSP90α mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker information

    The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.



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