Pepsinogen II (PG II) antibody and antigen (Recombinant protein)

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Diagnostic Pepsinogen II (PG II) antibodies (anti-Pepsinogen II, anti-PG II) and antigens (recombinant Pepsinogen II (PG II) protein) for Gastric disease PG II detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-PG-II-Ag01	Recombinant human PG II Protein	$3090.00
GMP-h-PG-II-Ab01	Anti-human PG II mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PG-II-Ab02	Anti-human PG II mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PG-II-Ab03	Anti-human PG II human monoclonal antibody (mAb)	$1953.00
GMP-h-PG-II-Ab04	Anti-human PG II human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Pruducts	GMP-h-PG-II-Ag01
Product Name	Recombinant human PG II Protein
Target/Biomarker	Pepsinogen II (PG II)
Alias of Target/Biomarker	#N/A
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Pepsinogen II (PG II) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation
Products description	Recombinant Human Pepsinogen II (PG II) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PG-II-Ab01,GMP-h-PG-II-Ab02
Product Name	Anti-human PG II mouse monoclonal antibody (mAb)
Target/Biomarker	Pepsinogen II (PG II)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human Pepsinogen II (PG II) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human PG II mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PG-II-Ab03,GMP-h-PG-II-Ab04
Product Name	Anti-human PG II human monoclonal antibody (mAb)
Target/Biomarker	Pepsinogen II (PG II)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human Pepsinogen II (PG II) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human PG II mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Pepsinogen II(PGII) - The Pepsinogens are gastric acid protease zymogens. They are divided into two distinct immunochemical groups. Pepsinogen I and II. Pepsinogen II is one of 4 aspartic proteinases: PG I, PG II, Cathepsin E and D. Pepsinogen II is produced primarily in the Oxyntic gland mucosa of the stomach, the gastric antrum and the duodenum. It is secreted mainly into the gastric lumen and into circulation. Pepsinogen II has little or no biological activity but in acid is converted to the active enzyme Pepsin which exhibits proteolytic actions. Unlike Pepsinogen I, Pepsinogen II is not normally found in the urine. Patients with pernicious anemia have low to non-detectable levels of Pepsinogen I but normal levels of Pepsinogen II. Pepsinogen II levels are slightly elevated in gastric ulcer. Patients with Zollinger-Ellison's syndrome exhibit greatly elevated levels.

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