Pepsinogen II (PG II) antibody and antigen (Recombinant protein)

Diagnostic Pepsinogen II (PG II) antibodies (anti-Pepsinogen II, anti-PG II) and antigens (recombinant Pepsinogen II (PG II) protein) for Gastric disease PG II detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-PG-II-Ag01 Recombinant human PGA5/PG II Protein 3090
GMP-h-PG-II-Ab01 Anti-human PGA5/PG II mouse monoclonal antibody (mAb) 1953
GMP-h-PG-II-Ab02 Anti-human PGA5/PG II mouse monoclonal antibody (mAb) 1953
GMP-h-PG-II-Ab03 Anti-human PGA5/PG II human monoclonal antibody (mAb) 1953
GMP-h-PG-II-Ab04 Anti-human PGA5/PG II human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-h-PG-II-Ag01
Product Name Recombinant human PGA5/PG II Protein
Target/Biomarker Pepsinogen II(PG II)
Alias of Target/Biomarker Pg5
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Pepsinogen II (PG II) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.
Products description Recombinant human PGA5/PG II Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-h-PG-II-Ab01, GMP-h-PG-II-Ab02
Product Name Anti-human PGA5/PG II mouse monoclonal antibody (mAb)
Target/Biomarker Pepsinogen II(PG II)
Alias of Target/Biomarker Pg5
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Pepsinogen II (PG II) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.
Tag mFc
Products description Anti-human PGA5/PG II mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-h-PG-II-Ab03, GMP-h-PG-II-Ab04
Product Name Anti-human PGA5/PG II human monoclonal antibody (mAb)
Target/Biomarker Pepsinogen II(PG II)
Alias of Target/Biomarker Pg5
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Pepsinogen II (PG II) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.
Tag hFc
Products description Anti-human PGA5/PG II human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Pepsinogen II(PGII) - The Pepsinogens are gastric acid protease zymogens. They are divided into two distinct immunochemical groups. Pepsinogen I and II. Pepsinogen II is one of 4 aspartic proteinases: PG I, PG II, Cathepsin E and D. Pepsinogen II is produced primarily in the Oxyntic gland mucosa of the stomach, the gastric antrum and the duodenum. It is secreted mainly into the gastric lumen and into circulation. Pepsinogen II has little or no biological activity but in acid is converted to the active enzyme Pepsin which exhibits proteolytic actions. Unlike Pepsinogen I, Pepsinogen II is not normally found in the urine. Patients with pernicious anemia have low to non-detectable levels of Pepsinogen I but normal levels of Pepsinogen II. Pepsinogen II levels are slightly elevated in gastric ulcer. Patients with Zollinger-Ellison's syndrome exhibit greatly elevated levels.



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    GDU

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    Comments


    Karen Wilson 2023-10-22 15:23:11
    This antigen is quite stable as well as it provides reliable results, which is quite suitable for Chemiluminescent Immunoassay (CLIA). It supports reliable diagnostics.

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