Procollagen III N-terminal peptide (PIIINP) antibody and antigen (Recombinant protein)

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Diagnostic Procollagen III N-terminal peptide (PIIINP) antibodies (anti-Procollagen III N-terminal peptide, anti-PIIINP) and antigens (recombinant Procollagen III N-terminal peptide (PIIINP) protein) for Liver diseases PIIINP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-PIIINP-Ag01	Recombinant human PIIINP Protein	$3090.00
GMP-h-PIIINP-Ab01	Anti-human PIIINP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PIIINP-Ab02	Anti-human PIIINP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PIIINP-Ab03	Anti-human PIIINP human monoclonal antibody (mAb)	$1953.00
GMP-h-PIIINP-Ab04	Anti-human PIIINP human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Pruducts	GMP-h-PIIINP-Ag01
Product Name	Recombinant human PIIINP Protein
Target/Biomarker	Procollagen III N-terminal peptide (PIIINP)
Alias of Target/Biomarker	#N/A
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Procollagen III N-terminal peptide (PIIINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PIIINP level test of Liver diseases (liver fibrosis and cirrhosis) and related syndrome evaluation
Products description	Recombinant Human Procollagen III N-terminal peptide (PIIINP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PIIINP-Ab01,GMP-h-PIIINP-Ab02
Product Name	Anti-human PIIINP mouse monoclonal antibody (mAb)
Target/Biomarker	Procollagen III N-terminal peptide (PIIINP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human Procollagen III N-terminal peptide (PIIINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Procollagen III N-terminal peptide (PIIINP) antibodies in PIIINP level test of Liver diseases (liver fibrosis and cirrhosis) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human PIIINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Procollagen III N-terminal peptide (PIIINP) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PIIINP-Ab03,GMP-h-PIIINP-Ab04
Product Name	Anti-human PIIINP human monoclonal antibody (mAb)
Target/Biomarker	Procollagen III N-terminal peptide (PIIINP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human Procollagen III N-terminal peptide (PIIINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Procollagen III N-terminal peptide (PIIINP) antibodies in PIIINP level test of Liver diseases (liver fibrosis and cirrhosis) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human PIIINP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Procollagen III N-terminal peptide (PIIINP), also known as Type III procollagen peptide, is a serum marker of collagen turnover and is used to assess hepatic fibrosis in patients on long-term Methotrexate. Background: PIIINP is the amino terminal peptide of type III procollagen, released from the precursor peptide during the synthesis and deposition of type III collagen. PIIINP in the serum can be derived from the synthesis of new type III collagen or from the degradation of existing type III collagen fibrils. There is evidence that serum PIIINP measurement is an effective non-invasive test for the detection and monitoring of Methotrexate-induced liver fibrosis and cirrhosis, and serial measurements may reduce the need for liver biopsy. Dermatology patients with repeated normal levels of PIIINP are very unlikely to have significant liver damage from fibrosis or cirrhosis. Conversely a high serum PIIINP or series of high values may indicate that a liver biopsy is required and in some cases, that Methotrexate should be withdrawn. Note that PIIINP can be raised following bone fracture and also in rheumatology patients as it can be falsely elevated in inflammatory arthritis.

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