S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibody and antigen (Recombinant protein)

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Diagnostic S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies (anti-S-adenosylhomocysteine (AdoHcy) hydrolase, anti-SAHH) and antigens (recombinant S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) protein) for Metabolic diseases SAHH detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-SAHH-Ag01	Recombinant human SAHH Protein	$3090.00
GMP-h-SAHH-Ab01	Anti-human SAHH mouse monoclonal antibody (mAb)	$1953.00
GMP-h-SAHH-Ab02	Anti-human SAHH mouse monoclonal antibody (mAb)	$1953.00
GMP-h-SAHH-Ab03	Anti-human SAHH human monoclonal antibody (mAb)	$1953.00
GMP-h-SAHH-Ab04	Anti-human SAHH human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Pruducts	GMP-h-SAHH-Ag01
Product Name	Recombinant human SAHH Protein
Target/Biomarker	S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH)
Alias of Target/Biomarker	SAHH, adoHcyase
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation
Products description	Recombinant Human protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-SAHH-Ab01,GMP-h-SAHH-Ab02
Product Name	Anti-human SAHH mouse monoclonal antibody (mAb)
Target/Biomarker	S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH)
Alias of Target/Biomarker	SAHH, adoHcyase
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human SAHH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-SAHH-Ab03,GMP-h-SAHH-Ab04
Product Name	Anti-human SAHH human monoclonal antibody (mAb)
Target/Biomarker	S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH)
Alias of Target/Biomarker	SAHH, adoHcyase
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human SAHH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

S-adenosylhomocysteine (AdoHcy) hydrolase (E.C.3.3.1.1) hydrolysis adenosine and homocysteine. In eukaryotes, this is the major route for disposal of the AdoHcy formed as a common product of each of many S-adenosylmethionine (AdoMet)-dependent methyltransferases. The reaction is reversible, but under normal conditions the removal of both adenosine and homocysteine is sufficiently rapid to maintain the flux in the direction of hydrolysis. AdoHcy is an inhibitor of many AdoMet-dependent methyltransferases. Thus, AdoHcy hydrolysis serves physiologically not only to sustain the flux of methionine sulfur toward cysteine, but is believed also to play a critical role in the regulation of biological methylations. The deficiency of AdoHcy leads to hypotonia with elevated serum creatine kinase and transaminases, prolonged prothrombin time and low albumin.

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