S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibody and antigen (Recombinant protein)
Diagnostic S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies (anti-S-adenosylhomocysteine (AdoHcy) hydrolase, anti-SAHH) and antigens (recombinant S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) protein) for Metabolic diseases SAHH detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-h-SAHH-Ag01 | Recombinant human AHCY/SAHH Protein | 3090 |
GMP-h-SAHH-Ab01 | Anti-human AHCY/SAHH mouse monoclonal antibody (mAb) | 1953 |
GMP-h-SAHH-Ab02 | Anti-human AHCY/SAHH mouse monoclonal antibody (mAb) | 1953 |
GMP-h-SAHH-Ab03 | Anti-human AHCY/SAHH human monoclonal antibody (mAb) | 1953 |
GMP-h-SAHH-Ab04 | Anti-human AHCY/SAHH human monoclonal antibody (mAb) | 1953 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. of Products | GMP-h-SAHH-Ag01 |
Product Name | Recombinant human AHCY/SAHH Protein |
Target/Biomarker | S-adenosylhomocysteine (AdoHcy) hydrolase(SAHH) |
Alias of Target/Biomarker | SAHH, adoHcyase |
Expression platform | mammalian |
Isotypes | Recombinant Antigen |
Bioactivity validation | S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation. |
Products description | Recombinant human AHCY/SAHH Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Products | GMP-h-SAHH-Ab01, GMP-h-SAHH-Ab02 |
Product Name | Anti-human AHCY/SAHH mouse monoclonal antibody (mAb) |
Target/Biomarker | S-adenosylhomocysteine (AdoHcy) hydrolase(SAHH) |
Alias of Target/Biomarker | SAHH, adoHcyase |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Human S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation. |
Tag | mFc |
Products description | Anti-human AHCY/SAHH mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Products | GMP-h-SAHH-Ab03, GMP-h-SAHH-Ab04 |
Product Name | Anti-human AHCY/SAHH human monoclonal antibody (mAb) |
Target/Biomarker | S-adenosylhomocysteine (AdoHcy) hydrolase(SAHH) |
Alias of Target/Biomarker | SAHH, adoHcyase |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Human S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation. |
Tag | hFc |
Products description | Anti-human AHCY/SAHH human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker information
S-adenosylhomocysteine (AdoHcy) hydrolase (E.C.3.3.1.1) hydrolysis adenosine and homocysteine. In eukaryotes, this is the major route for disposal of the AdoHcy formed as a common product of each of many S-adenosylmethionine (AdoMet)-dependent methyltransferases. The reaction is reversible, but under normal conditions the removal of both adenosine and homocysteine is sufficiently rapid to maintain the flux in the direction of hydrolysis. AdoHcy is an inhibitor of many AdoMet-dependent methyltransferases. Thus, AdoHcy hydrolysis serves physiologically not only to sustain the flux of methionine sulfur toward cysteine, but is believed also to play a critical role in the regulation of biological methylations. The deficiency of AdoHcy leads to hypotonia with elevated serum creatine kinase and transaminases, prolonged prothrombin time and low albumin.
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