Alpha-synuclein (α-synuclein) antibody and antigen (Recombinant protein)

Diagnostic Alpha-synuclein (α-synuclein) antibodies (anti-Alpha-synuclein, anti-α-synuclein) and antigens (recombinant Alpha-synuclein (α-synuclein) protein) for Neurodegenerative diseases α-synuclein detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-α-synuclein-Ag01 Recombinant human α-synuclein Protein $3090.00
GMP-h-α-synuclein-Ab01 Anti-human α-synuclein mouse monoclonal antibody (mAb) $1953.00
GMP-h-α-synuclein-Ab02 Anti-human α-synuclein mouse monoclonal antibody (mAb) $1953.00
GMP-h-α-synuclein-Ab03 Anti-human α-synuclein human monoclonal antibody (mAb) $1953.00
GMP-h-α-synuclein-Ab04 Anti-human α-synuclein human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-α-synuclein-Ag01
Product Name Recombinant human α-synuclein Protein
Target/Biomarker Alpha-synuclein (α-synuclein)
Alias of Target/Biomarker NACP, PARK1, PARK4, PD1, SNCA
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Alpha-synuclein (α-synuclein) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-synuclein level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Products description Recombinant Human Alpha-synuclein (α-synuclein) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-α-synuclein-Ab01,GMP-h-α-synuclein-Ab02
Product Name Anti-human α-synuclein mouse monoclonal antibody (mAb)
Target/Biomarker Alpha-synuclein (α-synuclein)
Alias of Target/Biomarker NACP, PARK1, PARK4, PD1, SNCA
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Alpha-synuclein (α-synuclein) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-synuclein (α-synuclein) antibodies in α-synuclein level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag mFc
Products description Anti-human α-synuclein mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-synuclein (α-synuclein) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-α-synuclein-Ab03,GMP-h-α-synuclein-Ab04
Product Name Anti-human α-synuclein human monoclonal antibody (mAb)
Target/Biomarker Alpha-synuclein (α-synuclein)
Alias of Target/Biomarker NACP, PARK1, PARK4, PD1, SNCA
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Alpha-synuclein (α-synuclein) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-synuclein (α-synuclein) antibodies in α-synuclein level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag hFc
Products description Anti-human α-synuclein mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker information

    Alpha-synuclein is a pre-synaptic protein that accumulates in Lewy bodies and Lewy neurites. The literature suggests that the concentration of α-synuclein in the CSF of individuals with Parkinson’s disease is below control levels. In contrast, levels of α-synuclein in the CSF were marginally higher in people with Alzheimer’s disease compared with controls (effect size = 1.183, p = 0.0004). It should be noted that the majority of AD cases in this analysis were diagnosed according to clinical criteria alone, and therefore it is not known to what extent comorbid Lewy body pathology was present. Likewise, it is unclear to what extent comorbid AD pathology may counteract the reported reduction of α-synuclein in the CSF of PD cases.



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