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Genemedi produces core diagnostic ingredients for test of Cardiovascular disease(intrinsic cardiac dysfunction) and related syndrome.

GeneMedi offers paired diagnostics grade pro B-type natriuretic peptide (proBNP) antibodies (monoclonal antibody,mab) and antigens for Cardiovascular disease(intrinsic cardiac dysfunction) rapid test kit of pro B-type natriuretic peptide (proBNP) testing in standard substance, positive control, ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

All the antibodies and antigens for Cardiovascular disease(intrinsic cardiac dysfunction) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used as positive control.

Heart ventricles produce B-type natriuretic peptide (BNP) in response to increased mechanical load and wall stretch. BNP protects the heart from adverse consequences of overload by increasing natriuresis and diuresis, relaxing vascular smooth muscle, inhibiting the renin-angiotensin-aldosterone system, and by counteracting cardiac hypertrophy and fibrosis. BNP is synthesized by cardiac myocytes as a 108-amino acid prohormone (proBNP), which is cleaved to the 32-residue BNP and the 76-residue N-terminal fragment of proBNP (NT-proBNP). Both can be used as sensitive biomarkers of cardiac dysfunction and well-characterized commercial assays have recently become available. In acute coronary syndromes increased concentrations are strong predictors of recurring myocardial infarction, heart failure, and death. In acute dyspnea, high BNP and NT-proBNP point to a cardiac rather than a pulmonary origin of the symptoms. BNP and NT-proBNP help in the assessment of the severity of ventricular dysfunction and heart failure and as a prognostic predictor, regardless of the primary cause of the condition. They can be used to guide the therapy of heart failure and left ventricular dysfunction. BNP and NT-proBNP work better when they are used for specific clinical purposes, rather than for screening in the general population. Their main strength is the excellent negative predictive value with regard to left ventricular dysfunction and heart failure. BNP and NT-proBNP are nonspecific biomarkers of cardiac dysfunction. Specific diagnostic tools, such as echocardiography, are required to define the actual abnormality.



Order information

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-h-proBNP-Ag01-1mg 1mg 3090
GMP-h-proBNP-Ag01-10mg 10mg 21890
GMP-h-proBNP-Ag01-100mg 100mg 148000
GMP-h-proBNP-Ab01-1mg 1mg 1953
GMP-h-proBNP-Ab01-10mg 10mg 13671
GMP-h-proBNP-Ab01-100mg 100mg 95697
GMP-h-proBNP-Ab02-1mg 1mg 1953
GMP-h-proBNP-Ab02-10mg 10mg 13671
GMP-h-proBNP-Ab02-100mg 100mg 95697
GMP-h-proBNP-Ag/Ab-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Cat No. of Pruducts GMP-h-proBNP-Ag01
Product Name Recombinant human proBNP Protein
Target pro B-type natriuretic peptide (proBNP)
Alias of Target/Biomarker BNP, Iso-ANP, NPPB
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation pro B-type natriuretic peptide (proBNP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in proBNP level test of Cardiovascular disease(intrinsic cardiac dysfunction) and related syndrome evaluation.
Tag His
Products description Recombinant Human pro B-type natriuretic peptide (proBNP) protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species NA
Purity Purity: ≥95% (SDS-PAGE)
Application Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-proBNP-Ab01, GMP-h-proBNP-Ab02
Product Name Anti-human proBNP mouse monoclonal antibody (mAb)
Target pro B-type natriuretic peptide (proBNP)
Alias of Target/Biomarker BNP, Iso-ANP, NPPB
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Human pro B-type natriuretic peptide (proBNP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other pro B-type natriuretic peptide (proBNP) antibodies in proBNP level test of Cardiovascular disease (intrinsic cardiac dysfunction) and related syndrome evaluation.
Tag mFc
Products description Anti-Human pro B-type natriuretic peptide (proBNP) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other pro B-type natriuretic peptide (proBNP) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.