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AAV serotype 1 (AAV capsid 1) system - Introduction

GeneMedi's AAV1 Rep-Cap plasmid (serotype 1-specific AAV RC plasmid), also named AAV1-RC plasmid, or AAV-RC1 plasmid, is part of AAV1 packaging system. AAV1 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV1 capsid protein.

You can produce AAV1 paticle in 293T cell line in high titer using GeneMedi's AAV1 Rep-Cap plasmid with GeneMedi's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

The tissue tropism of AAV1 vector has been validated in neuron(CNS), heart, muscle, retina and Pancreas, with potential applications in tissue-specific gene therapy.

Product Name Detail Price(In USD) Qty (Quantity) Sum(In USD)
AAV1 Rep-Cap Plasmid Serotype: AAV1
Size: 5ug
590
Shipping Cost: 360.00
Total:

AAV1 vector tissue tropism and gene transduction (serotype-specific AAV infection)

The tissue tropism of AAV1 vector has been validated in neuron(CNS), heart, muscle, retina and Pancreas, with potential applications in tissue-specific gene therapy.

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Figure. Selected transduction results of AAV in vitro (in 293T cell line)

Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml
Cells: HEK-293T
MOI: MOI=1×104
Determine assay: 36 hours post infection, immunofluorescence microscopy


Other AAV Rep-Cap Plasmid


AAV2 Rep-Cap Plasmid

AAV2-mu1 Rep-Cap Plasmid

AAV2-mu2 Rep-Cap Plasmid

AAV2-mu3 Rep-Cap Plasmid

AAV2-7m8 Rep-Cap Plasmid

AAV5 Rep-Cap Plasmid

AAV6 Rep-Cap Plasmid

AAV8 Rep-Cap Plasmid

AAV8-1m Rep-Cap plasmid

AAV8-2m Rep-Cap plasmid



AAV8 variant (Y733F, Y447F, Y275) Rep-Cap plasmid

AAV9 Rep-Cap Plasmid

AAV-Rh.10 Rep-Cap Plasmid

AAV-DJ Rep-Cap Plasmid

AAV-DJ/8 Rep-Cap Plasmid

AAV-Retro Rep-Cap Plasmid

AAV9-PHP.B Rep-Cap plasmid

AAV9-PHP.eB Rep-Cap plasmid

AAV9-PHP.S Rep-Cap plasmid