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AAV serotype Rh10 (AAV capsid Rh10) system - Introduction

GeneMedi's AAV-Rh10 Vector System (AAV serotype -Rh10 helper-free packaging plasmids system) is including AAV-Rh10 Rep-Cap plamid (AAV-Rh10-RC plasmid, or called AAV-RC-Rh10 plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).

GeneMedi's AAV expression vectors have been inserted with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas-Rh10-gRNA AAV expression vector.

AAV-Rh10 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV-Rh10 capsid protein.

The tissue tropism of AAV-Rh10 vector has been validated in neuron(CNS), lung, liver, heart and muscle, with potential applications in tissue-specific gene therapy.

Product Name Contents Price(In USD) Qty Sum(In USD)
AAV-Rh.10 vector system 1. AAV-Rh.10 Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. AAV CMV Expression Vector, 5ug
1060
Shipping Cost: 120.00
Total:

AAV serotype Rh10 (AAV capsid Rh10) system - Introduction

The tissue tropism of AAV-Rh10 vector has been validated in neuron(CNS), lung, liver, heart and muscle, with potential applications in tissue-specific gene therapy.

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Figure. Selected transduction results of AAV in vitro (in 293T cell line)

Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml
Cells: HEK-293T
MOI: MOI=1×104
Determine assay: 36 hours post infection, immunofluorescence microscopy


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AAV2 vector system

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AAV2 variant (Y272F, Y444F, Y500F, Y730F) vector system

AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector system

AAV2 variant (AAV2.7m8) vector system

AAV5 vector system

AAV6 vector system

AAV8 vector system

AAV8-1m vector system



AAV8-2m vector system

AAV8 variant (Y733F, Y447F, Y275F) vector system

AAV9 vector system

AAV-DJ vector system

AAV-Dj8 vector system

AAV2-Retro (Retrograde) vector system

AAV9-PHP.B vector system

AAV9-PHP.eB vector system

AAV9-PHP.S vector system