AAV-2i8 vector system (AAV-2i8 expression system, AAV-2i8 packaging plasmid system)

GeneMedi's AAV-2i8 Vector System (AAV serotype 2i8 helper-free packaging plasmids system) is including AAV-2i8 Rep-Cap plamid (AAV-2i8-RC plasmid, or called AAV-RC1 plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).

GeneMedi's AAV expression vectors have been inserted with differernt expression cassettes, containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.

AAV-2i8 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV-2i8 capsid protein.

The tissue tropism of AAV-2i8 vector has been validated in heart, liver, skeletal muscle, lung, kidney, brain, and retina with potential applications in tissue-specific gene therapy.