- • Up to 20%-50%* off first purchase
- • Bulk quantities available
- • Citation Reward application
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AAV-AAV4 Rep-Cap plasmid (serotype AAV4 - specific AAV RC-AAV4 plasmids)
GeneMedi's AAV4 Rep-Cap plasmid supplies the AAV2 Rep (replication) proteins and the AAV4 capsid protein.
You can produce AAV4 particle in 293T cell line in high titer using GeneMedi's AAV4 Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
The tissue tropism of AAV4 vector has been validated in lung and heart, as well as low transduction efficiency and viral genome copy numbers in the liver, with potential applications in tissue-specific gene therapy.
Go to AAV
vector system
>>Product Description
| Cat.NO | Product Name | Organization Type | Price(In USD) | ||
|---|---|---|---|---|---|
| P-RC27 | AAV4 Rep-Cap Plasmid | Academic | 2062 | ||
| P-RC27 | AAV4 Rep-Cap Plasmid | Industry R&D (excluding CRO&CDMO&CXO) |
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| P-RC27 | AAV4 Rep-Cap Plasmid |
CRO&CDMO& CXO&CMC& Manufacturing company |
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| P-RC27-Kan | AAV4 Rep-Cap Plasmid(Kan resistance) |
All | |||
| Currently, GeneMedi only offers amplification services for the Kan-resistant AAV Rep-Cap Plasmids and do not provide seed stocks. | |||||
| P-PK27 | AAV4 Vector
System
1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Academic | 3379 | ||
| P-PK27 | AAV4 Vector
System
1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Industry R&D (excluding CRO&CDMO&CXO) |
|||
| P-PK27 | AAV4 Vector
System
1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
|||
| P-PK27-Kan | AAV4 Vector
System(Kan resistance)
1. AAV4 Rep-Cap Plasmid(Kan resistance), 10mg 2. AAV Helper Plasmid(Kan resistance), 10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), 10mg |
All | |||
| Currently, GeneMedi only offers amplification services for the Kan-resistant AAV Vector System and do not provide seed stocks. | |||||
| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | |||||
|
Terms of sale: For Seed (5ug): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party. For plasmid production&lification (≥10mg): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party. |
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Citation
| Title | Publication | Date |
|---|---|---|
| HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation | Cell Discovery | 2023/8/15 |
| Chimeric antigen receptor-modified macrophages ameliorate liver fibrosis in preclinical models | Journal of Hepatology | 2024/2/8 |
| Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax | Kidney International | 2022/9/8 |
| CD8 T Cell-Derived Exosomal miR-186-5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis | Advanced Science | 2023/7/3 |
| Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence | Nature Communications | 2024/2/16 |
| Intestinal dysbiosis exacerbates susceptibility to the anti-NMDA receptor encephalitis-like phenotype by changing blood brain barrier permeability and immune homeostasis | Brain, Behavior, and Immunity | 2023/11/27 |
| SIRT6 protects vascular smooth muscle cell from osteogenic transdifferentiation via Runx2 in chronic kidney disease | Journal of Clinical Investigation | 2021/11/18 |
| Therapeutic reversal of Huntington's disease by in vivo self-assembled siRNAs | BRAIN | 2021/12/15 |
| NLRC3 Expression in Macrophage Impairs Glycolysis and Host Immune Defence by Modulating the NF-κB-NFAT5 Complex During Sepsis-induced Immunosuppression | Molecular Therapy | 2022/9/6 |
| Hepatic HuR modulates lipid homeostasis in response to high-fat diet | Nature Communications | 2020/6/16 |
Validation data
No data found
Associated products and services
| Products & Service | Products & Service Information |
|---|---|
| AAV Packaging service | Detail |
| Promise-ORF™ viral CDNA library | Detail |
| Plasmid DNA Rapid Preparation Service | Detail |
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