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AAV8-1m Rep-Cap plasmid (retina-validated serotype AAV-RC plasmid)
AAV protocol Download AAV User Manual Download Capsid mutant-AAV serotype 8 variant (AAV8-(Y733F) system - Introduction
GeneMedi's AAV8-1m Rep-Cap plasmid (retina-validated serotype AAV-RC plasmid), also named AAV8-1m-RC plasmid, is part of AAV8-1m packaging system. AAV8-1m Rep-Cap plamid supplies the AAV8 Rep(replication) proteins and the AAV8-1m capsid protein.
You can produce AAV8-1m paticle in 293T cell line in high titer using GeneMedi's AAV8-1m Rep-Cap plasmid with GeneMedi's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
The tissue tropism of AAV8 variant(Y733F) vector has been validated in retina with higher transduction efficiency and more rapid onset of expression in photoreceptor cells by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
| Product Name | Organization Type | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| AAV8-1m Rep-Cap plasmid Cat.No.:P-RC10 Serotype: AAV8-1m Size: 5ug | Academic | 1719 | ||
| AAV8-1m Rep-Cap plasmid Cat.No.:P-RC10 Serotype: AAV8-1m Size: 5ug | Industry R&D (excluding CRO&CDMO&CXO) | Inquiry | ||
| AAV8-1m Rep-Cap plasmid Cat.No.:P-RC10 Serotype: AAV8-1m Size: 5ug | CRO&CDMO& CXO&CMC& Manufacturing company | Inquiry | ||
| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | ||||
| Shipping Cost: | 169.00 | |||
| Total: | ||||
AAV8 capsid variant (Y733F) tissue tropism and gene transduction (serotype-specific AAV infection)
The tissue tropism of AAV8-1m vector has been validated in retina with higher transduction efficiency and more rapid onset of expression in photoreceptor cells by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml Cells: HEK-293T MOI: MOI=1×104 Determine assay: 36 hours post infection, immunofluorescence microscopy
Other AAV Rep-Cap Plasmid
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