- • Up to 20%-50%* off first purchase
- • Bulk quantities available
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AAV8 vector system (AAV8 expression system, AAV8 packaging plasmid system ) (Amp and Kanamycin) (GeneMedi Owned)
GeneMedi (GM) AAV8 Vector system is including: 1) AAV8 Rep-Cap plasmid (AAV8-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).
You can produce AAV8 particle in 293T cell line in high titer using GeneMedi's AAV8 Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
The tissue tropism of AAV8 vector has been validated in retina, liver, pancreas and muscle, with potential applications in tissue-specific gene therapy.
GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids, AAV expression Plasmids and AAV helper Plasmid.
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Product Description
| Cat.NO | Product Name | Organization Type | Price(In USD) | First Order Discount | First Order Discount Price |
|---|---|---|---|---|---|
| P-PK09 | AAV8 Vector System (Amp resistance) 1. AAV8 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Academic | 2028 | 50% | 1014 |
| P-PK09 | AAV8 Vector System (Amp resistance) 1. AAV8 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Biotech & Pharma & Medical Device & Diagnostics | 50% | ||
| P-PK09 | AAV8 Vector System (Amp resistance) 1. AAV8 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
50% | ||
| P-PK09 | AAV8 Vector System (Amp resistance) 1. AAV8 Rep-Cap Plasmid, ≥10mg 2. AAV Helper Plasmid, ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg |
All | |||
| P-PK09-Kan | AAV8 Vector System (Kan resistance) 1. AAV8 Rep-Cap Plasmid (Kan resistance) , ≥10mg 2. AAV Helper Plasmid (Kan resistance) , ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg |
All | |||
| P-RC09 | AAV8 Rep-Cap
Plasmid (Amp resistance)
Size：5ug |
Academic | 935 | 50% | 467.5 |
| P-RC09 | AAV8 Rep-Cap
Plasmid (Amp resistance)
Size：5ug | Biotech & Pharma & Medical Device & Diagnostics | 50% | ||
| P-RC09 | AAV8 Rep-Cap
Plasmid (Amp resistance)
Size：5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
50% | ||
| P-RC09 | AAV8 Rep-Cap
Plasmid (Amp resistance)
Size：≥10mg |
All | |||
| P-RC09-Kan | AAV8 Rep-Cap
Plasmid(Kan resistance)
Size：≥10mg |
All | |||
|
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System. GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently. |
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| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | |||||
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Terms of sale: For Seed (5ug): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party. For plasmid production& amplification (≥10mg): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party. |
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Citation
| Title | Publication | Date |
|---|---|---|
| Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy | CELL | 2017/7/27 |
| LINC02159 promotes non-small cell lung cancer progression via ALYREF/YAP1 signaling | Molecular Cancer | 2023/8/4 |
| Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1 | Molecular Cancer | 2023/7/17 |
| A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR | Molecular Cancer | 2023/1/23 |
| Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel | Nature Biomedical Engineering | 2023/3/23 |
| [PDF] GDF15 is a major determinant of ketogenic diet-induced weight loss | cell metabolism | 2023/12/5 |
| Skeletal muscle-derived extracellular vesicles transport glycolytic enzymes to mediate muscle-to-bone crosstalk | Cell Metabolism | 2023/11/7 |
| Lipid-accumulated reactive astrocytes promote disease progression in epilepsy | Nature Neuroscience | 2023/3/20 |
| TRIB3 Interacts with Beta-catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis | GASTROENTEROLOGY | 2018/10/11 |
| Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline | Cell Metabolism | 2020/3/3 |
Validation data
Figure. Selected transduction results of AAV in vitro (in 293T cell line)
Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml
Cells: HEK-293T
MOI: MOI=1×104
Determine assay: 36 hours post infection, immunofluorescence microscopy
Associated products and services
| Products & Service | Products & Service Information |
|---|---|
| AAV Packaging service | Detail |
| Promise-ORF™ viral CDNA library | Detail |
| Plasmid DNA Rapid Preparation Service | Detail |
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