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AAV serotype DJ8 (AAV capsid DJ8) system - Introduction

GeneMedi's AAV-DJ/8 Rep-Cap plasmid (serotype -DJ/8-specific AAV RC plasmid), also named AAV-DJ/8-RC plasmid, or AAV-RC-DJ/8 plasmid, is part of AAV-DJ/8 packaging system. AAV-DJ/8 Rep-Cap plamid supplies the AAV-DJ/8 Rep (replication) proteins and the AAV-DJ/8 capsid protein.

You can produce AAV-DJ/8 paticle in 293T cell line in high titer using GeneMedi's AAV-DJ/8 Rep-Cap plasmid with GeneMedi's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

AAV-DJ/8 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV-DJ/8 capsid protein.

The tissue tropism of AAV-DJ/8 vector has been validated in retina and liver, with potential applications in tissue-specific gene therapy.