Pre-made Talizumab benchmark antibody (Whole mAb, anti-IGHE/IgE therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Anti-IGHE/IgE therapeutic antibody (Pre-made Talizumab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Talizumab (TNX-91) is a humanized monoclonal antibody that was under development by Tanox in Houston, Texas as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils. Talizumab was tested in clinical trials at National Jewish Medical and Research Center and other medical centers and allergy clinics across the U. S. and shown to be able to prevent allergic reactions to accidental exposure to peanuts, which is contained in many kinds of foods.

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-1005-1mg	1mg	3090
GMP-Bios-INN-1005-10mg	10mg	Inquiry
GMP-Bios-INN-1005-100mg	100mg	Inquiry
GMP-Bios-INN-1005-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Talizumab Biosimilar, Whole Mab: Anti-Ighe/IgE therapeutic antibody
INN Name	Talizumab
Target	IGHE
Format	Whole mAb
Derivation	Humanized
Species Reactivity	human
CH1 Isotype	IgG1 - nd
VD LC	IgG1 - nd
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	MRC Technology (London UK) / Novartis Pharmaceuticals Corp. (East Hanover NJ USA) / Tanox Inc. (Houston TX USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	0