Pre-Made Corifollitropin Alfa Biosimilar, Fusion Protein targeting FSHR fused with CTP (C-terminal peptide of hCG): Recombinant therapeutic protein targeting FSHRO/LGR1/ODG1 for drug discovery and mechanism of action (MOA) research

Pre-Made Corifollitropin Alfa Biosimilar, Fusion Protein targeting FSHR fused with CTP (C-terminal peptide of hCG): Recombinant therapeutic protein targeting FSHRO/LGR1/ODG1 is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women.[1] There are also recombinant variants.

Corifollitropin alfa (Elonva®) is the first hybrid follicle-stimulating hormone (FSH) molecule with demonstrated sustained follicle-stimulating activity. Corifollitropin combines follicle stimulating hormone with part of the human chorionic gonadotropin molecule. This extends the time to peak serum concentration and approximately doubles the half-life for the treatment of infertility.

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-788-1mg	1mg	3090
GMP-Bios-INN-788-10mg	10mg	Inquiry
GMP-Bios-INN-788-100mg	100mg	Inquiry
GMP-Bios-INN-788-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Corifollitropin Alfa Biosimilar, Fusion Protein targeting FSHR fused with CTP (C-terminal peptide of hCG): Recombinant therapeutic protein targeting FSHRO/LGR1/ODG1
INN Name	Corifollitropin Alfa
Target	FSHR
Format	Fusion Protein
Derivation	human
Species Reactivity	human
CH1 Isotype	Fusion - Follicle- stimulating hormone (FSH) - CTP (C-terminal peptide of the β- subunit of human chorionic gonadotropin (hCG))
VD LC	Fusion - Follicle- stimulating hormone (FSH) - CTP (C-terminal peptide of the β- subunit of human chorionic gonadotropin (hCG))
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	Merck & Co., Inc. (Whitehouse Station NJ USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	0