Products
Oregovomab Biosimilar Monoclonal Antibody (MUC16) for Research
Anti-MUC16 therapeutic antibody (Pre-made Oregovomab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Oregovomab (marketed under the trade name OvaRex) is a mouse monoclonal antibody it binds to the antigen CA125, a carbohydrate antigen. It is designed for the treatment of ovarian cancer.[1]
Order Information
| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-940-1mg | 1mg | 3090 |
| GMP-Bios-INN-940-10mg | 10mg | |
| GMP-Bios-INN-940-100mg | 100mg | |
| GMP-Bios-INN-940-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Oregovomab Biosimilar, Whole Mab, Anti-Muc16 Antibody: Anti-CA125 therapeutic antibody |
| INN Name | Oregovomab |
| Target | MUC16 |
| Format | Whole mAb |
| Derivation | Mus musculus |
| Species Reactivity | human |
| CH1 Isotype | IgG1 - kappa |
| VD LC | IgG1 - kappa |
| Highest_Clin_Trial (Jan '20) | |
| Est. Status | |
| 100% SI Structure | |
| 99% SI Structure | |
| 95-98% SI Structure | |
| Year Proposed | |
| Year Recommended | |
| Companies | AltaRex Corp. (Edmonton AB Canada) |
| Conditions Approved | |
| Conditions Active | |
| Conditions Discontinued | |
| Development Tech | 0 |
About target - MUC16
1. Protein Mucin-16
2. Gene MUC16
3. Organism Homo sapiens (Human)
Function
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Miscellaneous
Antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer. Due to lack of sensitivity for stage I disease and lack of specificity, it is of little value in the detection of early ovarian cancer. Due to its similarly elevated levels in some nonmalignant conditions, it is not specific enough to be used for population screening.
