Pre-made Rovalpituzumab Tesirine benchmark antibody (Whole mAb ADC, anti-DLL3 therapeutic antibody, Anti-SCDO1 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-INN-980

Pre-made Rovalpituzumab Tesirine benchmark antibody (Whole mAb ADC, anti-DLL3 therapeutic antibody, Anti-SCDO1 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Rovalpituzumab tesirine (Rova-T) is an experimental antibody-drug conjugate targeting the protein DLL3 on tumor cells.[1][2] It was originally developed by Stemcentrx and was purchased by AbbVie.[3] It was tested for use in small-cell lung cancer, but development was terminated after unsuccessful phase III trial.[4][5]

Order information


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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-INN-980-1mg 1mg Inquiry
GMP-Bios-INN-980-10mg 10mg Inquiry
GMP-Bios-INN-980-100mg 100mg Inquiry
GMP-Bios-INN-980-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Rovalpituzumab Tesirine Biosimilar, Whole Mab Adc, Anti-Dll3 Antibody: Anti-SCDO1 therapeutic antibody Drug Conjugate
INN Name Rovalpituzumab Tesirine
TargetDLL3
FormatWhole mAb ADC
DerivationHumanized
Species Reactivityhuman
CH1 IsotypeIgG1 - kappa
VD LCIgG1 - kappa
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
CompaniesStemcentrx, Inc. (San Francisco CA USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech0